Results 31 to 40 of about 146,941 (286)

The long-term effects of genomic selection: 1. Response to selection, additive genetic variance, and genetic architecture

open access: yesGenetics Selection Evolution, 2022
Background Genomic selection has revolutionized genetic improvement in animals and plants, but little is known about its long-term effects. Here, we investigated the long-term effects of genomic selection on response to selection, genetic variance, and ...
Yvonne C. J. Wientjes   +5 more
doaj   +1 more source

Cancer-inspired Genomics Mapper Model for the Generation of Synthetic DNA Sequences with Desired Genomics Signatures [PDF]

open access: yes, 2023
Genome data are crucial in modern medicine, offering significant potential for diagnosis and treatment. Thanks to technological advancements, many millions of healthy and diseased genomes have already been sequenced; however, obtaining the most suitable data for a specific study, and specifically for validation studies, remains challenging with respect
arxiv   +1 more source

Heterosis and Hybrid Crop Breeding: A Multidisciplinary Review

open access: yesFrontiers in Genetics, 2021
Although hybrid crop varieties are among the most popular agricultural innovations, the rationale for hybrid crop breeding is sometimes misunderstood. Hybrid breeding is slower and more resource-intensive than inbred breeding, but it allows systematic ...
Marlee R. Labroo   +2 more
doaj   +1 more source

GplusE: beyond genomic selection [PDF]

open access: yesFood and Energy Security, 2015
AbstractGplusE is a strategy for genomic selection in which the accuracy of assessment in the reference population for a primary trait such as yield is increased by the incorporation of data from high‐ throughput field phenotyping platforms. This increase in precision comes from both exploiting genetic relationships between traits and reducing the ...
Mackay, I, Ober, E, Hickey, John
openaire   +3 more sources

A simulation framework for reciprocal recurrent selection-based hybrid breeding under transparent and opaque simulators

open access: yesFrontiers in Plant Science, 2023
Hybrid breeding is an established and effective process to improve offspring performance, while it is resource-intensive and time-consuming for the recurrent process in reality.
Zerui Zhang   +4 more
doaj   +1 more source

Enrichment of gut microbiome strains for cultivation-free genome sequencing using droplet microfluidics [PDF]

open access: yesCell Reports Methods 12/2021, 2021
We report a droplet microfluidic method to target and sort individual cells directly from complex microbiome samples, and to prepare these cells for bulk whole genome sequencing without cultivation. We characterize this approach by recovering bacteria spiked into human stool samples at a ratio as low as 1:250 and by successfully enriching endogenous ...
arxiv   +1 more source

Genetic control of tomato fruit quality: from QTL mapping to Genome Wide Association studies and breeding

open access: yesComptes Rendus Biologies, 2022
Consumers began to complain about the taste of tomato varieties in the late 1990’s. Although tomato taste is influenced by environmental and post-harvest conditions, varieties show a large diversity for fruit quality traits. We herein review our past and
Causse, Mathilde   +10 more
doaj   +1 more source

Genomics Select [PDF]

open access: yesCell, 2007
The incredible leaps in technology that now make high-speed genome sequencing possible are revolutionizing the hunt for genes and genetic variations associated with disease. A stunning series of recent genome-wide association studies (GWAS) have identified new candidate genes for a number of common diseases including breast cancer, heart disease ...
openaire   +1 more source

Combining detection and reconstruction of correlational and quasi-periodic motifs in viral genomic sequences with transitional genome mapping: Application to COVID-19 [PDF]

open access: yesJournal of Integrated OMICS, 2021, v.11(1) p.5-11, 2020
A method of Transitional Automorphic Mapping of the Genome on Itself (TAMGI) is aimed at combining detection and reconstruction of correlational and quasi-periodic motifs in the viral genomic RNA/DNA sequences. The motifs reconstructed by TAMGI are robust with respect to indels and point mutations and can be tried as putative therapeutic targets.
arxiv   +1 more source

Genomics Select [PDF]

open access: yesCell, 2009
Genomic plasticity is emerging as a mechanism of phenotypic variation both within individual organisms and across species over evolutionary time. This Genomics Select examines recently reported examples of genomic plasticity at work as well as the mechanisms for how one mode of genome alteration, transposition, is regulated.
openaire   +1 more source

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