Results 31 to 40 of about 244,292 (287)

Challenges of SARS-CoV-2 genomic surveillance in India during low positivity rate scenario

Frontiers in Public Health, 2023
Being the second most populous country in the world, India presents valuable lessons for the world about dealing with the SARS-CoV-2 pandemic. From this perspective, we attempted a retrospective evaluation of India’s SARS-CoV-2 genomic surveillance ...
Siddharth Singh Tomar, Siddharth Singh Tomar, Krishna Khairnar, Krishna Khairnar   +3 more
doaj   +1 more source

Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa [PDF]

, 2014
Substantial amounts of data have been generated from patient management and academic exercises designed to better understand the human immunodeficiency virus (HIV) epidemic and design interventions to control it.
Bester, Armand, Chetty, Terusha, Danaviah, Siva, De Oliveira, Tulio, Goedhals, Dominique, Iwuji, Collins, Lessells, Richard, Manasa, Justen, McGrath, Nuala, Moodley, Pravi, Naidu, Kevindra, Rossouw, Theresa, Seebregts, Christopher J, Singh, Lavanya, Skingsley, Andrew, Stott, Katharine, Van Vuuren, Cloete, Van Zyl, Gert   +17 more
core   +3 more sources

Strengthening pathogen genomic surveillance for health emergencies: insights from the World Health Organization’s regional initiatives

Frontiers in Public Health, 2023
The onset of the COVID-19 pandemic triggered a rapid scale-up in the use of genomic surveillance as a pandemic preparedness and response tool. As a result, the number of countries with in-country SARS-CoV-2 genomic sequencing capability increased by 40 ...
Oluwatosin Wuraola Akande, Lisa L. Carter, Abdinasir Abubakar, Rachel Achilla, Amal Barakat, Nicksy Gumede, Alina Guseinova, Francis Yesurajan Inbanathan, Masaya Kato, Etien Koua, Juliana Leite, Marco Marklewitz, Jairo Mendez-Rico, Chavely Monamele, Biran Musul, Karen Nahapetyan, Dhamari Naidoo, Rachel Ochola, Mehmet Ozel, Philomena Raftery, Andrea Vicari, Pushpa Ranjan Wijesinghe, Joanna Zwetyenga, Kelly Safreed-Harmon, Céline Barnadas, Mick Mulders, Dmitriy I. Pereyaslov, Jilian A. Sacks, Taylor Warren, Sébastien Cognat, Sylvie Briand, Gina Samaan   +31 more
doaj   +1 more source

Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing

Frontiers in Cellular and Infection Microbiology, 2022
The Trachypithecus leucocephalus (white-headed langur) is a highly endangered, karst-endemic primate species, inhabiting the karst limestone forest in Guangxi, Southwest China.
Tengcheng Que, Xianwu Pang, Xianwu Pang, Hongli Huang, Panyu Chen, Yinfeng Wei, Yiming Hua, Hongjun Liao, Jianbao Wu, Shousheng Li, Aiqiong Wu, Meihong He, Xiangdong Ruan, Yanling Hu, Yanling Hu   +14 more
doaj   +1 more source

MHC-I genotype drives early immune selection of oncogenic mutations. [PDF]

, 2018
MHC-I exposes the intracellular contents to immune cells for surveillance of cellular health. Due to high genomic variation, individuals' immune systems differ in their ability to expose and eliminate cancer-causing mutations.
Carter, Hannah, de Prisco, Nicola, Font-Burgada, Joan, Marty, Rachel   +3 more
core   +1 more source

CLIMB-COVID: continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance

Genome Biology, 2021
In response to the ongoing SARS-CoV-2 pandemic in the UK, the COVID-19 Genomics UK (COG-UK) consortium was formed to rapidly sequence SARS-CoV-2 genomes as part of a national-scale genomic surveillance strategy.
Samuel M. Nicholls, Radoslaw Poplawski, Matthew J. Bull, Anthony Underwood, Michael Chapman, Khalil Abu-Dahab, Ben Taylor, Rachel M. Colquhoun, Will P. M. Rowe, Ben Jackson, Verity Hill, Áine O’Toole, Sara Rey, Joel Southgate, Roberto Amato, Rich Livett, Sónia Gonçalves, Ewan M. Harrison, Sharon J. Peacock, David M. Aanensen, Andrew Rambaut, Thomas R. Connor, Nicholas J. Loman, The COVID-19 Genomics UK (COG-UK) Consortium   +23 more
doaj   +1 more source

Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]

, 2020
We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM, Hinds, J, Hossain, I, Hua, Y, Mackenzie, GA, Manna, S, Mulholland, EK, Ndiaye, M, Ortika, BD, Salaudeen, R, Satzke, C   +10 more
core   +4 more sources

Toward a global virus genomic surveillance network

Cell Host & Microbe, 2023
The COVID-19 pandemic galvanized the field of virus genomic surveillance, demonstrating its utility for public health. Now, we must harness the momentum that led to increased infrastructure, training, and political will to build a sustainable global genomic surveillance network for other epidemic and endemic viruses.
Hill, Verity, Githinji, George, Vogels, Chantal B.F., Bento, Ana I., Chaguza, Chrispin, Carrington, Christine V.F., Grubaugh, Nathan D.   +6 more
openaire   +2 more sources

Evaluation of WGS-subtyping methods for epidemiological surveillance of foodborne salmonellosis [PDF]

, 2020
Background: Salmonellosis is one of the most common foodborne diseases worldwide. Although human infection by non-typhoidal Salmonella (NTS) enterica subspecies enterica is associated primarily with a self-limiting diarrhoeal illness, invasive bacterial ...
Mohammed, M., Mohammed, M., Thapa, S., Thapa, S.   +3 more
core   +1 more source

High Genetic Diversity of Carbapenem-Resistant Acinetobacter baumannii Isolates Recovered in Nigerian Hospitals in 2016 to 2020

mSphere, 2023
Acinetobacter baumannii causes difficult-to-treat infections mostly among immunocompromised patients. Clinically relevant A. baumannii lineages and their carbapenem resistance mechanisms are sparsely described in Nigeria. This study aimed to characterize
Erkison Ewomazino Odih, Anderson O. Oaikhena, Anthony Underwood, Yaovi Mahuton Gildas Hounmanou, Oyinlola O. Oduyebo, Abayomi Fadeyi, Aaron O. Aboderin, Veronica O. Ogunleye, Silvia Argimón, Vitus Nnaemeka Akpunonu, Phillip O. Oshun, Abiodun Egwuenu, Tochi J. Okwor, Chikwe Ihekweazu, David M. Aanensen, Anders Dalsgaard, Iruka N. Okeke   +16 more
doaj   +1 more source