Results 181 to 190 of about 5,806,293 (254)

Dietary Flavonoid Hyperoside Ameliorates High‐Fat Diet‐Induced Type 2 Diabetes Mellitus by Enhancing Brown Adipose Tissue Thermogenesis, White Adipose Tissue Browning, and Gut Microbiota Remodeling

Phytotherapy Research, EarlyView.
Hyperoside ameliorates metabolic dysfunction in high‐fat diet‐induced type 2 diabetic mice, accompanied by enhanced brown adipose tissue thermogenic activity, inguinal white adipose tissue browning‐related changes, reduced M1 macrophage polarization, and gut microbiota remodeling.
WeiFeng Cai, WenXin Zeng, Yu Luo, Qiang Liu, CuiPing Jiang, YanKui Yi, JieYu Chen, ChunYan Shen   +7 more
wiley   +1 more source

Pre-Infusion Host-Marrow Vulnerability in CD19- and BCMA-Directed CAR T-Cell Therapy: Clonal Hematopoiesis, Hematotoxicity, and Therapy-Related Myeloid Neoplasia. [PDF]

Cancer Manag Res
Liu Y, Su G, Li R, Wang S.
europepmc   +1 more source

Polypyrrole Nanofibrous Aerogel for Pressure Sensing and Anionic Contaminant Remediation

Small, EarlyView.
Nanofibrous aerogels (NFAs), highly porous ultralow‐density networks of entangled nanofibers, are conformally coated with polypyrrole (PPy) to provide a multifaceted material platform. Leveraging NFA's high surface area and mechanically robust structure with the conductive properties of PPy enables pressure‐responsive sensing for flexible electronics ...
Muhammed Ziauddin Ahmad Ebrahim, Ilaria Napoletano, Anicah Smith O'Brien, Tahira Pirzada, Saad A. Khan   +4 more
wiley   +1 more source

From infection to cholangiocarcinoma: Why opisthorchiids break these rules. [PDF]

One Health
Heneberg P.
europepmc   +1 more source

Context‐Dependent Radioenhancement by Platinum Nanoparticles Under Conventional and Ultra‐High Dose‐Rate “FLASH” Radiotherapy

Small, EarlyView.
Overview of the experimental workflow and main findings of the study investigating Pt‐NPs‐mediated radioenhancement under conventional 134 dose‐rate (CONV) and ultrahigh dose‐rate (UHDR) 9 MeV electron irradiation. Pt‐NP distribution and uptake were characterized in 4T1 spheroids and syngeneic tumor models.
Cathyanne Schott, Foutina Feghali, Marine Gerbé de Thoré, Amina Joudat, Lydia Meziani, Aashini Rajpal, Winchygn Liu, Tudor Manoliu, Farah Savina, Sandrine Lacombe, Eric Deutsch, Julie Colnot, Charlotte Robert, Erika Porcel, Pauline Maury   +14 more
wiley   +1 more source

Biochemical, Genotoxic and Somatic responses of Oreochromis Niloticus Exposed to Enalapril Maleate in Water. [PDF]

Bull Environ Contam Toxicol
da Silva AKP, Colaço OAW, Mannes Y, Ramsdorf WA.   +3 more
europepmc   +1 more source

Detection and Inhalation Hazard Assessment of Wear Particles Arising From Abrasion of Market‐relevant Graphene Reinforced Composites

Small, EarlyView.
Abrasion of few‐layer graphene (FLG)–epoxy composites generated respirable particles in which FLG remained fully embedded, as confirmed by correlative HR‑TEM, Raman, and ToF‑SIMS analyses. Advanced lung cell models revealed no cytotoxic or inflammatory responses, and only high‑dose epoxy particles reduced mucociliary clearance.
Govind Gupta, Jimmy Vernaz, Antje Vennemann, Maike Stange, Asmus Meyer‐Plath, Servane Contal, Sarah Zehnder, Ziting Wang, Aline Chary, Stephanie Eitner, Philipp Mueller, Vera M. Kissling, Samuel Constant, Lucie Chupin, Daniel Breitenstein, Birgit Hagenhoff, Tommaso Serchi, Bernadett Boda, Martin Wiemann, Peter Wick, Tina Buerki‐Thurnherr   +20 more
wiley   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

EZH2 Inhibition and Myeloid Risk: A Feature of On-Target Biology. [PDF]

Clin Cancer Res
Alumkal JJ, Ellis L.
europepmc   +1 more source

Human‐Centered Monitoring of Asphalt Emissions: Linking Exposure, Climate, and Health

Safety Science and Technology, EarlyView.
A human‐centered framework linking heat‐driven asphalt emissions to real‐world exposure, biological response, and functional health outcomes, highlighting how climate‐sensitive infrastructure can become a measurable, manageable source of urban environmental and health risk. ABSTRACT Urban infrastructure shapes environmental quality not only through its
Suliman Rashid, Hessam Yazdani, Jessica Verpeut, Shiva Pooladvand, Vajiheh Akbarzadeh, Ali Shamshiripour, Elham H. Fini   +6 more
wiley   +1 more source