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Synthesis of Metal and Metal Oxide Nanoparticles by Flame Spray Pyrolysis and Safety Assessment. [PDF]

open access: yesToxics
Efthimiou I   +5 more
europepmc   +1 more source
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Perspectives On The Genotoxic Risk Of Styrene

Journal of Toxicology and Environmental Health, Part B, 2005
Styrene is a highly reactive monomer widely used in the plastics industry. The potential for styrene to produce genotoxic effects has been studied extensively in experimental systems. Styrene can induce sister chromatid exchanges (SCE) and chromosome aberrations (CA) in vitro under test conditions that enhance metabolism of styrene to styrene 7,8-oxide
E R, Nestmann, B S, Lynch, F, Ratpan
openaire   +2 more sources

Mode of action-based risk assessment of genotoxic carcinogens [PDF]

open access: yesArchives of Toxicology, 2020
AbstractThe risk assessment of chemical carcinogens is one major task in toxicology. Even though exposure has been mitigated effectively during the last decades, low levels of carcinogenic substances in food and at the workplace are still present and often not completely avoidable.
Sabine Guth   +2 more
exaly   +8 more sources

Risk assessment of non-genotoxic carcinogens

Toxicology Letters, 1992
Rates of cell proliferation, cell death, and cell differentiation affect the risk of cancer profoundly. An increase in cell proliferation rates leads to an increase in mutation rates per unit of time, which, in turn, leads to an increase in the risk of cancer.
S H, Moolgavkar, E G, Luebeck
openaire   +2 more sources

Approaches to the risk assessment of genotoxic carcinogens in food: A critical appraisal [PDF]

open access: yesFood and Chemical Toxicology, 2006
The present paper examines the particular difficulties presented by low levels of food-borne DNA-reactive genotoxic carcinogens, some of which may be difficult to eliminate completely from the diet, and proposes a structured approach for the evaluation of such compounds.
A G Renwick, W Slob, J Van Benthem
exaly   +5 more sources

Genotoxicity risk assessment: a proposed classification strategy

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2002
Recent advances in genetic toxicity (mutagenicity) testing methods and in approaches to performing risk assessment are prompting a renewed effort to harmonize genotoxicity risk assessment across the world. The US Environmental Protection Agency (EPA) first published Guidelines for Mutagenicity Risk Assessment in 1986 that focused mainly on ...
Kerry L, Dearfield   +4 more
openaire   +2 more sources

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