Results 81 to 90 of about 36,448 (257)
Environmental Health, 2011 Background We hypothesized that in Flanders (Belgium), the prevalence of at-risk genotypes for genotoxic effects decreases with age due to morbidity and mortality resulting from chronic diseases. Rather than polymorphisms in single genes, the interaction
van Delft Joost HM +11 more
doaj +1 more source
Chemical Risks, Genotoxicity, and Oxidative Stress in Healthcare Workers
ToxicsBackground/Objectives Using genotoxicity tests and oxidative stress indicators, the study evaluated the relationship between healthcare workers’ (HCWs) exposure to chemical risks. This study aimed to evaluate the oxidative damage and genotoxic effects of sub chronic or long-term volatile organic compounds (VOCs) exposure in HCWs.
Beyan, Ayşe Coşkun +3 more
openaire +3 more sources
Food Safety and Health, EarlyView.This review elucidates the formation pathways and detection technologies for ethyl carbamate, biogenic amines, and higher alcohols in Huangjiu. It concludes that integrated control frameworks are essential to decouple safety risks from the metabolic processes responsible for flavor development.
Lulu Liu +5 more
wiley +1 more source
Food Safety and Health, EarlyView.Industrial manufacturing processes have transformative effects on the components of food matrix. These transformations in food matrix and components have direct implications for quality assurance (QA), food quality (e.g., nutritional profile and texture), and food safety management (e.g., pathogen control and toxin mitigation). ABSTRACT This systematic
Chinaza Godswill Awuchi
wiley +1 more source
Investigating the cytotoxicity and genotoxicity of Vortioxetine with in vivo and in silico methods
Scientific ReportsVortioxetine is a multimodal antidepressant with reported benefits on cognitive functioning, social functioning, and fatigue, however its potential genotoxic risks have not been adequately studied.
Meliha Merve Çicekliyurt +4 more
doaj +1 more source
Evaluation of genotoxic and cytotoxic effects of anorectic drugs in lymphocytes of obese people
Revista Brasileira de Obesidade, Nutrição e Emagrecimento, 2019 Obesity is a major public health concern nowadays, as the risk of developing cancer and other chronic diseases has increased considerably in this population.
Cristiano José da Silva +2 more
doaj
International Journal of Cancer, EarlyView.Colorectal cancer incidence and mortality have increased in the Asia‐Pacific region over the past three decades. This population‐based study in Taiwan suggests a shift of the colorectal cancer burden towards the younger generations. An age–period–cohort model revealed higher annual increases in incidence (3.58%) and mortality (1.0%) rates among ...
Yun‐Chen Tsai +3 more
wiley +1 more source
Environmental carcinogens often exacerbate endogenous mutagenic processes to enhance tumor promotion
Cell ReportsSummary: Environmental exposures significantly influence cancer risk, but their mutational impact remains unclear. We perform whole-exome sequencing of hepatocellular carcinomas (HCCs) from B6C3F1/N mice that arise spontaneously with age (2 years old) or
Miaofei Xu +13 more
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International Journal of Cancer, EarlyView.ABSTRACT Esophageal adenocarcinoma (EAC) exhibits marked male predominance with male‐to‐female ratios reaching 8.5:1, yet the molecular basis underlying this sex disparity remains poorly characterized. We analyzed 92 EAC specimens using mass spectrometry–based proteomics, comprising 47 female and 45 male tumors from treatment‐naïve patients ...
Alexander Quaas +8 more
wiley +1 more source
Update of the risk assessment on emerging and novel brominated flame retardants in food
EFSA JournalThe European Commission asked EFSA to update its 2012 risk assessment on Emerging and Novel brominated flame retardants (BFRs) in food. Since the previous Opinion, further information was collected for a total of 27 BFRs.
EFSA Panel on Contaminants in the Food Chain (CONTAM) +33 more
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