Results 81 to 90 of about 5,806,293 (254)
Assessing the genotoxic damage among farming community: identifying and prioritizing the associated risk factors [PDF]
, 2016 Objective: This study aims at determining the association between the genotoxic damage with various risk factors among farmers and the children from the pesticide treated rice farming village in a tropical country.
Ismail, Patimah +4 more
core +1 more source
Precision medicine in paediatrics: Progress and priorities
British Journal of Clinical Pharmacology, EarlyView.Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain +3 more
wiley +1 more source
, 2018 Humans are exposed to chemical compounds in everyday life, both from the environment and from endogenous processes. Some compounds constitute a risk for cancer development. One such compound is glycidol, which is genotoxic and an animal carcinogen. It is
Aasa, Jenny
core +1 more source
Genotoxic and mutagenic effects of triterpenes: A mini-review
, 2017 This review sketches genotoxic and mutagenic potentials of triterpenes, which find outs some important genotoxic, mutagenic as well as non-genotoxic and non-mutagenic triterpenes. Triterpeners are the important natural products.
Muhammad Islam
core +1 more source
Biotechnology and Bioengineering, EarlyView.Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga +2 more
wiley +1 more source
Genotoxic risk in humans and acute toxicity in rats of a novel oral high-dose coenzyme Q10 oleogel. [PDF]
Toxicol Rep, 2021 Masotta NE +5 more
europepmc +1 more source
BMEMat, EarlyView.This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao +3 more
wiley +1 more source
Genotoxic risk assessment and mechanism of DNA damage induced by phthalates and their metabolites in human peripheral blood mononuclear cells. [PDF]
Sci Rep, 2021 Sicińska P +4 more
europepmc +1 more source
Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis. [PDF]
, 2014 Based on the process of carcinogenesis, carcinogens are classified as either genotoxic or non-genotoxic. In contrast to non-genotoxic carcinogens, many genotoxic carcinogens have been reported to cause tumor in carcinogenic bioassays in animals.
Seul Ji Lee (517836) +24 more
core +1 more source
BMEMat, EarlyView.Oral microbial homeostasis, a dynamic host‐microbe balance, is vital in infectious diseases. Conventional antibiotics often disrupt this homeostasis, spurring interest in nanomaterials for oral microbial homeostasis rebalancing. This review outlines nanomaterial strategies across three ecological levels (population/community, ecosystem, and cross ...
Chen Hu +10 more
wiley +1 more source