Results 101 to 110 of about 35,705 (247)

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, EarlyView.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Capillary Zone Electrophoresis for the Analysis of Phenolic Preservatives in Plasma and Insulin Formulations Using Salting‐Out Assisted Liquid–Liquid Extraction

open access: yesELECTROPHORESIS, EarlyView.
A rapid and reliable SALLE–CZE–UV method was developed for the determination of phenolic preservatives in insulin formulations and human plasma. The approach provides efficient extraction, fast separation (< 6 min), and excellent sensitivity, precision, and recovery, meeting regulatory requirements for accurate quantification.
Meriem Dadouch   +2 more
wiley   +1 more source

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert   +5 more
wiley   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo   +7 more
wiley   +1 more source

Optimizing the encapsulation of Lactiplantibacillus plantarum and Lactobacillus acidophilus for enhanced storage stability and gut viability using spray drying

open access: yesFood Biomacromolecules, EarlyView.
Abstract This research aimed to enhance the storage stability and functional potential of Lactobacillus acidophilus and Lactiplantibacillus plantarum through encapsulation using the spray drying technique. The probiotics were encapsulated with 10% carrier materials—corn starch, maltodextrin, and Acacia gum—combined with the prebiotic fructo ...
Kanimozhi Viswanathan, Sukumar Muthusamy
wiley   +1 more source

Mitigating Health Risks in French Fries: Understanding Acrylamide and Hydroxymethylfurfural Management Through Potato Variety and Storage Exploration

open access: yesFuture Postharvest and Food, EarlyView.
Strategic optimization of potato variety selection and storage conditions to control harmful compounds in French fries. Through systematic evaluation of three potato varieties stored under conditions upto 45 days, which demonstrated that Kufri Frysona variety stored for 15 days provides the best balance between minimizing health‐risk compounds and ...
Vandana Verma   +3 more
wiley   +1 more source

Canned Foods: Evolution, Benefits, and Health Implications of Modern Packaging

open access: yesFood Safety and Health, EarlyView.
This graphical abstract presents a concise visual overview of canned food technology, highlighting its historical evolution, key benefits, and associated health risks. It integrates timelines, icons, and summary points to clearly communicate advancements in preservation, consumer advantages, and potential safety concerns in a single schematic ...
Shaswati Rout   +3 more
wiley   +1 more source

Toxic Metals in Dried Marine Fish and Implications for Human Health in Bangladesh and Exporting Countries

open access: yesFood Safety and Health, EarlyView.
This study assessed toxic metals in five dried marine fish species from Bangladesh. Although most metals were within safe limits, chromium (Cr) consistently exceeded FAO/WHO standards, especially at Kuakata Beach. The findings highlight localized contamination hotspots and species‐specific bioaccumulation, while risk assessment supports the safety and ...
Shapla Khatun   +7 more
wiley   +1 more source

Aloe vera in Food Preservation: Harnessing Bioactive Constituents for Clean‐Label Innovation and Safety Assurance

open access: yesFood Safety and Health, EarlyView.
Aloe vera‐derived biopolymers and nanoformulations enhance antimicrobial, antioxidant, and barrier functions in clean‐label edible coatings and films, whereas safety‐critical anthraquinone thresholds and regulatory constraints shape their translational potential.
Acharya Balkrishna   +6 more
wiley   +1 more source

Influence of Nanomaterials and Nanocomposites on the Nutrient Composition

open access: yesFood Safety and Health, EarlyView.
Nanomaterials and nanocomposites enhance crop nutrition and food quality by improving nutrient availability, plant uptake, and bioavailability through controlled delivery and nano‐encapsulation. Their applications in agriculture and food systems enable sustainable biofortification, improved preservation, and functional foods, while emphasizing safety ...
Akanksha Dwivedi   +4 more
wiley   +1 more source

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