Results 101 to 110 of about 89,616 (295)
Dental Research Journal, 2012 Background: The greater surface of bioactive glass nanoparticles presents an incomparable and promising feature similar to the biological apatite. Nanoparticles improve cellular adhesion, enhance osteoblast proliferation and differentiation, and increase
Mohammad Tavakoli +8 more
doaj +1 more source
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Assessment of Polycyclic Aromatic Hydrocarbon Contamination of Breeding Pools Utilized by the Puerto Rican Crested Toad, Peltophryne lemur. [PDF]
, 2012 Habitat preservation and management may play an important role in the conservation of the Puerto Rican crested toad, Peltophryne lemur, due to this species' small geographic range and declining native wild population. Bioavailable water concentrations of
De Voe, Ryan +3 more
core +3 more sources
Advanced Synthesis &Catalysis, EarlyView.A mild, scalable electrocatalytic method for direct lactonization of benzylic alcohols to phthalides using N‐hydroxyphthalimide as a redox mediator is reported. This metal‐free process proceeds via a phthalimide‐N‐oxyl‐mediated hydrogen atom transfer mechanism, shows broad scope with good to excellent yields, and enables late‐stage functionalizations ...
Pietro Ronco +6 more
wiley +1 more source
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1:a novel anticancer small-molecule [PDF]
, 2015 Restoration of the p53 pathway, namely by reactivation of mutant (mut) p53, represents a valuable anticancer strategy. Herein, we report the identification of the enantiopure tryptophanol-derived oxazoloisoindolinone SLMP53-1 as a novel reactivator of ...
Bessa, Cláudia +15 more
core +3 more sources
Safe‐and‐Sustainable‐by‐Design Approach and Decision Support System for Advanced Materials
Advanced Sustainable Systems, EarlyView.The HARMLESS Safe‐and‐Sustainable‐by‐Design (SSbD) approach and SSbD‐Decision Support System (DSS) guide designers through a workflow of three tools providing design and assessment advice. By adapting the data and resource requirements to each innovation stage, the SSbD‐DSS facilitates practical implementation of SSbD, supporting the user to find a ...
Susan Dekkers +11 more
wiley +1 more source
Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats [PDF]
, 2006 Recent epidemiological studies suggest that high meat intake is associated with promotion of colon cancer linked to haem-iron intake. We previously reported that dietary haem, in the form of either haemoglobin or meat, promotes precancerous lesions in ...
Guéraud, Françoise +5 more
core +1 more source
Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors
Advanced Science, EarlyView.Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen +4 more
wiley +1 more source
ATR-FTIR spectroscopy detects alterations induced by organotin(IV) carboxylates in MCF-7 cells at sub-cytotoxic/-genotoxic concentrations. [PDF]
, 2008 The environmental impact of metal complexes such as organotin(IV) compounds is of increasing concern. Genotoxic effects of organotin(IV) compounds (0.01 μg/ml, 0.1 μg/ml or 1.0 μg/ml) were measured using the alkaline single-cell gel electrophoresis ...
Ahmad, Muhammad S. +6 more
core +3 more sources