Results 201 to 210 of about 63,628 (254)

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Heavy Metal-Induced Genotoxic Damage in <i>Chelon auratus</i>: Evidence from a Coastal Gulf Ecosystem. [PDF]

Toxics
Turan C, Ergenler A, Koç ZA, Turan F.
europepmc   +1 more source

Novel nitro‐quinoline photoinitiators for composites: exploring the effects of hydroxyl and methacrylate substituents on the photopolymerization of dimethacrylate matrices

Polymer International, EarlyView.
New quinoline derivatives proved to be efficient photoinitiators for dental resin monomers under two different light‐curing units, yielding favorable conversion, color and fluorescence results in the presence of different co‐initiators, including an eco‐friendly alternative.
Vitor Fernandes Moreno, Luiz Carlos da Silva‐Filho, Adilson Yoshio Furuse   +2 more
wiley   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

The GENOMARK biomarker inhuman HepaRGTM cells: a new approach methodology for genotoxicity assessment

, 2023
L. van Grunsven, T. Vanhaecke, A. Thienpont, B. Mertens, S. Verhulst, V. Rogiers   +5 more
core  

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du, Shikai Yan, Xiaopeng Ren, Syed Shams ul Hassan, Yuanfang Sun, Yu Gan, Xue Xiao, Shasha Li, Huizi Jin   +8 more
wiley   +1 more source

Phytochemical profiling and pharmacological evaluation of <i>Fingerhuthia africana</i> lehm: radical-scavenging behavior, genotoxicity, and antidiarrheal activities. [PDF]

Front Pharmacol
Ullah H, Adil M, Zhang C.
europepmc   +1 more source

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

Comprehensive safety assessment of novel dicholine folate vitamin. [PDF]

Toxicol Rep
Jonaitis T, Ulmann M, Wiesler G, Lukasik KV.   +3 more
europepmc   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source