Results 41 to 50 of about 35,705 (247)

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Effects of artichoke (Cynara scolymus) leaf and bloom head extracts on chemically induced DNA lesions in Drosophila melanogaster

Genetics and Molecular Biology, 2014
The genotoxicity of bloom head (BHE) and leaf (LE) extracts from artichoke (Cynara scolymus L.), and their ability to modulate the mutagenicity and recombinogenicity of two alkylating agents (ethyl methanesulfonate - EMS and mitomycin C - MMC) and the ...
Laura Vicedo Jacociunas, Rafael Rodrigues Dihl, Mauricio Lehmann, Alexandre de Barros Falcão Ferraz, Marc François Richter, Juliana da Silva, Heloísa Helena Rodrigues de Andrade   +6 more
doaj   +1 more source

A comparative genotoxicity study of a supraphysiological dose of triiodothyronine (T₃) in obese rats subjected to either calorie-restricted diet or hyperthyroidism. [PDF]

PLoS ONE, 2013
This study was designed to determine the genotoxicity of a supraphysiological dose of triiodothyronine (T3) in both obese and calorie-restricted obese animals.
Maria Teresa De Sibio, Renata Azevedo Melo Luvizotto, Regiane Marques Castro Olimpio, Camila Renata Corrêa, Juliana Marino, Miriane de Oliveira, Sandro José Conde, Ana Lúcia dos Anjos Ferreira, Carlos Roberto Padovani, Célia Regina Nogueira   +9 more
doaj   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source

Genotoxic and antigenotoxic medicinal plant extracts and their main phytochemicals: “A review”

Frontiers in Pharmacology
Many medicinal plant extracts have been proven to have significant health benefits. In contrast, research has shown that some medicinal plant extracts can be toxic, genotoxic, mutagenic, or carcinogenic.
Ghanya Al-Naqeb, Ghanya Al-Naqeb, Aliki Kalmpourtzidou, Francesca Giampieri, Francesca Giampieri, Rachele De Giuseppe, Hellas Cena, Hellas Cena   +7 more
doaj   +1 more source

Summarized data of genotoxicity tests for designated food additives in Japan

Genes and Environment, 2018
The Ministry of Health, Labour and Welfare has carried out genotoxicity tests for food additives used in Japan in cooperation with the Japan Food Additives Association since 1979. Hayashi et al.
Masami Yamada, Masamitsu Honma
doaj   +1 more source

Few-layer graphene induces both primary and secondary genotoxicity in epithelial barrier models in vitro

Journal of Nanobiotechnology, 2021
Background Toxicological evaluation of engineered nanomaterials (ENMs) is essential for occupational health and safety, particularly where bulk manufactured ENMs such as few-layer graphene (FLG) are concerned.
Michael J. Burgum, Martin J. D. Clift, Stephen J. Evans, Nicole Hondow, Afshin Tarat, Gareth J. Jenkins, Shareen H. Doak   +6 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Genotoxicity assessment of chemical mixtures

EFSA Journal, 2019
The EFSA Scientific Committee addressed in this document the peculiarities related to the genotoxicity assessment of chemical mixtures. The EFSA Scientific Committee suggests that first a mixture should be chemically characterised as far as possible ...
EFSA Scientific Committee, Simon More, Vasileios Bampidis, Diane Benford, Jos Boesten, Claude Bragard, Thorhallur Halldorsson, Antonio Hernandez‐Jerez, Susanne Hougaard‐Bennekou, Kostas Koutsoumanis, Hanspeter Naegeli, Søren Saxmose Nielsen, Dieter Schrenk, Vittorio Silano, Dominique Turck, Maged Younes, Gabriele Aquilina, Riccardo Crebelli, Rainer Gürtler, Karen Ildico Hirsch‐Ernst, Pasquale Mosesso, Elsa Nielsen, Roland Solecki, Maria Carfì, Carla Martino, Daniela Maurici, Juan Parra Morte, Josef Schlatter   +27 more
doaj   +1 more source

Genotoxicity and cytotoxicity induced by eluates from orthodontic glass ionomer cements in vitro

Saudi Dental Journal, 2018
The aim of this study was to investigate genotoxicity and cytotoxicity of some orthodontic glass ionomer cements commercially available by means of the single cell gel (comet) assay.
Fernanda Angelieri, Yuri Slusarenko da Silva, Daniel Araki Ribeiro   +2 more
doaj   +1 more source