Peculiarities of Tlr-2 (Arg753gln) and Tlr-4 (Asp299gly) Polymorphism Prevalence in Patients with Acute Brucelleis and Cardiovascular System Diseases [PDF]
, 2019 Currently, there are single data on the relationship between TLR-2 polymorphisms (Arg753Gln) and TLR-4 (Asp299Gly) polymorphisms and susceptibility to brucellosis.
Huseynov, E. M. (Elchin)
core
Host genotype and age shape the leaf and root microbiomes of a wild perennial plant
Nature Communications, 2016 Bacteria living on and in leaves and roots influence many aspects of plant health, so the extent of a plant’s genetic control over its microbiota is of great interest to crop breeders and evolutionary biologists.
Maggie R. Wagner +5 more
semanticscholar +1 more source
Genotyping-by-Sequencing in Plants [PDF]
Biology, 2012 The advent of next-generation DNA sequencing (NGS) technologies has led to the development of rapid genome-wide Single Nucleotide Polymorphism (SNP) detection applications in various plant species. Recent improvements in sequencing throughput combined with an overall decrease in costs per gigabase of sequence is allowing NGS to be applied to not only ...
Stéphane Deschamps +2 more
openaire +3 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Beijing Lineage of MDR Mycobacterium tuberculosis in Bulgaria, 2007–2011
Emerging Infectious Diseases, 2014 To assess the spread of the Mycobacterium tuberculosis Beijing genotype among patients with multidrug-resistant and extensively resistant tuberculosis in Bulgaria, we genotyped 188 (72%) of 261 microbiologically confirmed resistant isolates obtained ...
Stefan Panaiotov +10 more
doaj +1 more source
How does SCYLV genetic diversity impact on Sugarcane disease resistance and breeding? [PDF]
, 2012 To date, six distinct genotypes of the Sugarcane yellow leaf virus have been described in the literature (BRA, CUB, CHN1, IND, PER and REU). However, little information is available regarding the impact of virus genetic diversity on disease resistance ...
Daugrois, Jean-Heinrich +1 more
core
Evolutionary dynamics of the most populated genotype on rugged fitness landscapes
, 2007 We consider an asexual population evolving on rugged fitness landscapes which are defined on the multi-dimensional genotypic space and have many local optima.
C. L. Burch +18 more
core +1 more source
Performance of assays for testing antibodies against porcine reproductive and respiratory syndrome virus in sera collected from swine farms in a region with an extreme virus heterogeneity [PDF]
, 2014 Porcine reproductive and respiratory syndrome is the most economically important viral disease in the swine industry worldwide. Porcine reproductive and respiratory syndrome virus (PRRSV) strains are classified into two distinct genotypes, the European ...
Karniychuk, U Uladzimir, Nauwynck, Hans
core +2 more sources
Genome Research, 2011 Copy number variation (CNV) in the genome is a complex phenomenon, and not completely understood. We have developed a method, CNVnator, for CNV discovery and genotyping from read-depth (RD) analysis of personal genome sequencing.
A. Abyzov +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source