Results 61 to 70 of about 1,921,022 (384)

ACC Synthase Genes Related to Cold-dependent Ripening in Pear Fruit [PDF]

, 2004
The differential regulation of ACC synthase genes has been studied in pear cultivars that either require a long chilling treatment before they are capable of ripening (‘Passe-Crassane’, PC) or not (‘Old-Home’, OH) and in OH x PC hybrids having no (A16)
El-Sharkawy, Islam, Latché, Alain, Lelièvre, Jean-Marc, Pech, Jean-Claude   +3 more
core   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Genetic diversity and distance among Iranian and European alfalfa (Medicago sativa L.) genotypes [PDF]

, 2011
Alfalfa is the best known fodder crop with high ability of biological nitrogen fixation and drought tolerance in dry, Pannonian region of east Austria.
Ardakani, M.Reza, Friedel, Juergen K., Moghaddam, Ali, Pietsch, Gabriele, Raza, Amir, Vollmann, Johann   +5 more
core  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Static and Evolving Norovirus Genotypes: Implications for Epidemiology and Immunity

PLoS Pathogens, 2017
Noroviruses are major pathogens associated with acute gastroenteritis worldwide. Their RNA genomes are diverse, with two major genogroups (GI and GII) comprised of at least 28 genotypes associated with human disease.
G. I. Parra, R. B. Squires, Consolee K Karangwa, Jordan A. Johnson, C. Lepore, S. Sosnovtsev, K. Green   +6 more
semanticscholar   +1 more source

THE ROLE OF DNA-METHYLTRANSFERASES IN THE LIFE CYCLE OF HEPATITIS B VIRUS AND PATHOGENESIS OF CHRONIC HEPATITIS B

Вопросы вирусологии, 2018
Chronic hepatitis B is caused by a persistent form of hepatitis B virus, covalently closed circular DNA (cccDNA). Stability of cccDNA is associated with intracellular localization of cccDNA and formation of minichromosome, regulated by epigenetic ...
D. S. Kostyushev, A. P. Zueva, S. A. Brezgin, A. D. Lipatnikov, E. V. Volchkova, V. V. Maleyev, V. P. Chulanov   +6 more
doaj   +1 more source

Potential des Anbaus von Saflor (Carthamus tinctorius L.) unter den Bedingungen des Ökologischen Landbaus in Mitteleuropa [PDF]

, 2005
Under organic farming conditions, twenty safflower genotypes were tested for genotype-by-environment interaction (GxE) and stability across four locations in Germany and Switzerland for seed yield and oil content..
Claupein, Wilhelm, Elfadl, Elfadl Yousif, Reinbrecht, Carsten, von Witzke-Ehbrecht, Sabine   +3 more
core  

Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia [PDF]

, 2017
Interactions between killer-immunoglobulin-like receptors (KIRs) and their HLA class I ligands are instrumental in natural killer (NK) cell regulation and protect normal tissue from NK cell attack.
Aurelius, J., Bernson, E., Brune, M., Foà, R., Hallner, A., Hellstrand, K., Kiffin, R., Martner, A., Rydström, A., Sander, F. E., Thorén, F. B., Werlenius, O., Wilsson, O.   +12 more
core   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Sofosbuvir and ribavirin in HCV genotypes 2 and 3.

New England Journal of Medicine, 2014
BACKGROUND In clinical trials, treatment with a combination of the nucleotide polymerase inhibitor sofosbuvir and the antiviral drug ribavirin was associated with high response rates among patients with hepatitis C virus (HCV) genotype 2 infection, with ...
S. Zeuzem, G. Dusheiko, R. Salupere, A. Mangia, R. Flisiak, R. Hyland, A. Illeperuma, E. Svarovskaia, D. Brainard, W. Symonds, G. Subramanian, J. Mchutchison, O. Weiland, H. Reesink, P. Ferenci, C. Hézode, R. Esteban   +16 more
semanticscholar   +1 more source