Results 61 to 70 of about 1,309,818 (329)

Current epidemiological, molecular and genetic characteristics of enteric viral hepatitis in Russia

Alʹmanah Kliničeskoj Mediciny, 2018
Rationale: Enteric hepatitis including hepatitis A and hepatitis E are globally prevalent diseases with large social and economic burden. In some patient categories these may be lethal.
E. V. Esaulenko, A. A. Sukhoruk, A. D. Bushmanova, T. Ingabire, Yu. V. Ostankova   +4 more
doaj   +1 more source

Genetic diverstiy of Sugarcane yellow leaf virus in a sugarcane selection plot in Guadeloupe (FWI) [PDF]

, 2010
THE GENETIC diversity of Sugarcane yellow leaf virus (SCYLV) was investigated in a sugarcane selection plot in Guadeloupe to determine the incidence of the different known virus genotypes (BRA-PER, CUB and REU) in a breeding progeny.
Daugrois, Jean-Heinrich, Fernandez, Emmanuel, Girard, Jean-Claude, Roques, Danièle, Rott, Philippe, Roumagnac, Philippe   +5 more
core  

Eggplant and related species are promising genetic resources to dissect the plant immune response to Pseudomonas syringae and Xanthomonas euvesicatoria and to identify new resistance determinants [PDF]

, 2014
The apparent lack of durability of many resistance (R) genes highlights the need for the constant identification of new genetic sources of resistance for the breeding of new disease-resistant crop cultivars.
Clarke, Christopher R., Hayes, Byron W., Runde, Brendan J., Vinatzer, Boris A., Wicker, Emmanuel   +4 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Assessing Resistance in Maize Genotypes to Banded Leaf and Sheath Blight (Rhizoctonia solani f. sp. sasakii) under Artificial Epiphytotic Condition

Turkish Journal of Agriculture: Food Science and Technology
Maize (Zea mays L.), the second principal cereal crop in Nepal, faces severe yield constraints due to biotic stressors, notably banded leaf and sheath blight (BLSB), a fungal pathogen incited by Rhizoctonia solani f. sp. sasakii.
Bibek Phulara, Shishir Sharma, Suk Bahadur Gurung, Bibek Acharya, Hrithik Khati   +4 more
doaj   +1 more source

Steatosis in chronic hepatitis B: Prevalence and correlation with biochemical, histologic, viral, and metabolic parameters

Indian Journal of Pathology and Microbiology, 2011
Background and Aims: Hepatic steatosis (HS) is highly prevalent in chronic hepatitis C and is an important variable predicting progression of histological injury, insulin resistance, and reduced response to antiviral therapy. There are limited data on HS
Archana Rastogi, Puja Sakhuja, Ashish Kumar, Syed Hissar, Akshat Jain, Ranjana Gondal, Shiv Kumar Sarin   +6 more
doaj   +1 more source

Circular 82 [PDF]

, 1991
The development of improved plant cultivars is accomplished through comprehensive plant breeding programs. Such programs: 1) evaluate genetically-diverse germplasm in order to identify superior-performing genotypes; 2) create new genetic ...
Blake, Steve A., Dofing, Stephen M., Knight, Charles W.   +2 more
core  

Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections. [PDF]

, 2015
Arenaviruses are one of the largest families of human hemorrhagic fever viruses and are known to infect both mammals and snakes. Arenaviruses package a large (L) and small (S) genome segment in their virions.
Chang, Li-Wen, DeRisi, Joseph L, Drazenovich, Tracy, Dunker, Freeland, Fisher, Debbie, Guzman, David S-M, Hawkins, Michelle G, Jacobson, Elliott R, Kamaka, Elizabeth K, Levens, Gregory, Meola, Linda F, Reavill, Drury R, Sanders, Chris, Stenglein, Mark D   +13 more
core   +3 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source