Results 291 to 300 of about 58,106,402 (334)

Genetic diversity, population structure, and phylogeny of insular Spanish pepper landraces (Capsicum annuum L.) through phenotyping and genotyping-by-sequencing. [PDF]

Front Plant Sci
Ortega-Albero N, Barchi L, Fita A, Díaz M, Martínez F, Luna-Prohens JM, Rodríguez-Burruezo A.   +6 more
europepmc   +1 more source

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

A genomic dataset integrating genotyping-by-sequencing, SolCAP array and PCR marker data on tetraploid potato advanced breeding lines. [PDF]

Front Plant Sci
Leuenberger J, Sharma SK, Sharma SK, McLean K, Pellé R, Bérard A, Lesage ML, Porhel D, Dantec MA, Chauvin JE, Bryan GJ, Pilet-Nayel ML, Kerlan MC, Esnault F.   +13 more
europepmc   +1 more source

Genome-Wide Genetic Diversity and Population Structure of Charybdis feriata (Crustacea, Decapoda, and Portunidae) Along the Southeast Coast of China Inferred from Genotyping-by-Sequencing (GBS) Approach. [PDF]

Genes (Basel)
He J, Wu J, Wan L, Xu W, Yang T.
europepmc   +1 more source

Mapping broad-spectrum virus resistance in Brassica rapa using an advantageous tandem genotyping by sequencing approach

Bramham L, Barker G, Walsh J.
europepmc   +1 more source

Methods for Genotyping-by-Sequencing.

Methods in molecular biology, 2017
A major goal for biologists is to understand the connection between genes and phenotypic traits, and genetic mapping in experimental populations remains a powerful approach for discovering the causal genes underlying phenotypes.
Beth A. Rowan, Danelle K. Seymour, E. Chae, D. Lundberg, D. Weigel   +4 more
semanticscholar   +5 more sources

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Random PCR-Based Genotyping by Sequencing Technology GRAS-Di (Genotyping by Random Amplicon Sequencing, Direct) Reveals Genetic Structure of Mangrove Fishes

Molecular Ecology Resources, 2019
While various technologies for high‐throughput genotyping have been developed for ecological studies, simple methods tolerant to low‐quality DNA samples are still limited.
Sho Hosoya, Shotaro Hirase
exaly   +2 more sources

Genotyping-by-Sequencing.

Current Protocols in Plant Biology, 2017
AbstractGenotyping‐by‐sequencing (GBS) refers to a suite of related methods that obtain genotype data from samples by using restriction enzyme digestion followed by high‐throughput sequencing. GBS is a refinement of restriction site–associated DNA sequencing (RADseq) methods, with a goal of being able to perform library preparations quickly, cost ...
Jason G. Wallace, S. Mitchell
semanticscholar   +3 more sources

Genotyping-by-Sequencing on the Ion Torrent Platform in Barley.

Methods in molecular biology, 2018
The characterization of genetic polymorphism is a crucial step in both genetic studies and breeding programs. Genotyping-by-sequencing (GBS) constitutes one of the most attractive approaches for this purpose, especially in a genome as large as that of barley.
Amina Abed, Gaétan Légaré, Sonia Pomerleau, J. St.-Cyr, B. Boyle, F. Belzile   +5 more
semanticscholar   +4 more sources

Genotyping-by-Sequencing in Ecological and Conservation Genomics [PDF]

Molecular Ecology, 2013
The fields of ecological and conservation genetics have developed greatly in recent decades through the use of molecular markers to investigate organisms in their natural habitat and to evaluate the effect of anthropogenic disturbances. However, many of these studies have been limited to narrow regions of the genome, allowing for limited inferences but
Michael R Miller, John W Davey, Shawn R Narum   +2 more
exaly   +3 more sources