Results 71 to 80 of about 181,932 (222)
Integrating sequencing datasets to form highly confident SNP and indel genotype calls for a whole human genome [PDF]
, 2013 Clinical adoption of human genome sequencing requires methods with known accuracy of genotype calls at millions or billions of positions across a genome. Previous work showing discordance amongst sequencing methods and algorithms has made clear the need for a highly accurate set of genotypes across a whole genome that could be used as a benchmark.
arxiv +1 more source
rfPhen2Gen: A machine learning based association study of brain imaging phenotypes to genotypes [PDF]
arXiv, 2022 Imaging genetic studies aim to find associations between genetic variants and imaging quantitative traits. Traditional genome-wide association studies (GWAS) are based on univariate statistical tests, but when multiple traits are analyzed together they suffer from a multiple-testing problem and from not taking into account correlations among the traits.
arxiv
Melioidosis Caused by Burkholderia pseudomallei in Drinking Water, Thailand, 2012
Emerging Infectious Diseases, 2014 We identified 10 patients in Thailand with culture-confirmed melioidosis who had Burkholderia pseudomallei isolated from their drinking water. The multilocus sequence type of B.
Direk Limmathurotsakul +10 more
doaj +1 more source
Genotype networks, innovation, and robustness in sulfur metabolism [PDF]
arXiv, 2010 Metabolic networks are complex systems that comprise hundreds of chemical reactions which synthesize biomass molecules from chemicals in an organism's environment. The metabolic network of any one organism is encoded by a metabolic genotype, defined by a set of enzyme-coding genes whose products catalyze the network's reactions. Each metabolic genotype
arxiv
Splitting pairs and the number of clusters generated by random pair incompatibilities [PDF]
arXiv, 2007 We consider a random fitness landscape on the space of haploid diallelic genotypes with n genetic loci, where each genotype is considered either inviable or viable depending on whether or not there are any incompatibilities among its allele pairs. We suppose that each allele pair in the set of all possible allele pairs on the n loci is independently ...
arxiv
Existence of traveling waves for the generalized FKPP equation [PDF]
arXiv, 2016 Variation in genotypes may be responsible for differences in dispersal rates, directional biases, and growth rates of individuals. These traits may favor certain genotypes and enhance their spatio-temporal spreading into areas occupied by the less advantageous genotypes.
arxiv
Structural and Biochemical Properties of Duckweed Surface Cuticle
Frontiers in Chemistry, 2018 The plant cuticle, which consists of cutin and waxes, forms a hydrophobic coating covering the aerial surfaces of all plants. It acts as an interface between plants and their surrounding environment whilst also protecting them against biotic and abiotic ...
Nikolai Borisjuk +9 more
doaj +1 more source
Genotyping coronavirus SARS-CoV-2: methods and implications [PDF]
arXiv, 2020 The emerging global infectious COVID-19 coronavirus disease by novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and the economy since it was identified in late December 2019 in China. The virus has gone through various pathways of evolution.
arxiv
Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang +16 more
wiley +1 more source
Agronomy, 2017 This study examines aspects of virulence to resistant rice varieties among planthoppers and leafhoppers. Using a series of resistant varieties, brown planthopper, Nilaparvata lugens, virulence was assessed in seedlings and early-tillering plants at seven
Finbarr G. Horgan +11 more
doaj +1 more source