Results 121 to 130 of about 171,280 (266)

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

Small, EarlyView.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji, Zhuozhuo Wu, Yuyue Jiang, Xiaoyu Liu, Jingfeng Li, Fengkuo Xu, Chaojie Li, Qungang Shan, Ziyin Wang, Junhao Wang, Wei Huang, Yaping Zhuang, Wenguo Cui, Zhongmin Wang   +13 more
wiley   +1 more source

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

Small, EarlyView.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova, Olivera Valentirović Dann, Jennifer B. Schwarzkopf, Tengku I. Maulana, Jamina S. Gerhardus, Leon Kaysan, Katja Meier, Andreas Blaeser, Beate K. Straub, Holger Gerhardt, Ulrike A. Nuber   +10 more
wiley   +1 more source

Efficacy of Vitex pseudo-negundo in a Bovine Mastitis Model Experimentally Induced by Staphylococcus aureus in Rats. [PDF]

Vet Med Sci
Koç H, Fındık A, Güvenç T, Batan N, Fandaklı S, Fındık M.   +5 more
europepmc   +1 more source

Remote‐Controlled Release of Nitric Oxide by Plasmonic Waveguide Coated With Metal–Organic Frameworks

Small, EarlyView.
Remote‐controlled intracellular delivery is achieved using a plasmonic waveguide coated with a photoresponsive NO‐releasing MOF. Surface plasmon polariton propagation remotely induces photocleavage and localized nitric oxide release in a target single live cell without direct light exposure, while biological relevance is demonstrated through transient ...
Tomoko Inose, Javier Lopez‐Cabrelles, Javier Troyano, Shun Tokuda, Elí Sánchez‐González, Nobuaki Takahashi, Yasuo Mori, Kenji Hirai, Hiroshi Uji‐i, Shuhei Furukawa   +9 more
wiley   +1 more source

Differential modulation of gentamicin antibacterial activity by vitamin B12 and vitamin D3 against Gram-positive and Gram-negative bacteria: an <i>in vitro-in silico</i> study. [PDF]

Ann Med
M'hamedi I, Zatla I, Benelhadj-Djelloul S, Kara-Terki I, Bellifa S, Boublenza L.   +5 more
europepmc   +1 more source

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

Ups and downs in the experimental treatment of murine typhoid fever using gentamicin combined with caffeine. [PDF]

Braz J Microbiol
de Souza Silva E, Dos Santos Rocha RT, da Silva JNG, Ribeiro VVP, Ponte IS, Fraga ICB, de Oliveira CSA, Lima Galvão VM, Silva AHJ, da Silva Junior VA, Lima-Filho JV.   +10 more
europepmc   +1 more source

Protective Effects of Bee Venom (Apis mellifera) Against Cadmium‐Induced Hepatorenal Toxicity, Oxidative Stress, and Anxiety‐Like Behavior in Rats

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a persistent environmental heavy metal and a major public health concern because it persists in the body for long periods and gradually accumulates in vital organs, particularly the liver, kidneys, and brain. Chronic Cd exposure promotes the excessive production of reactive oxygen species (ROS), which ultimately leads to ...
Soumaya Ghodbane, Chedli Ellijimi, Rym Elfessi, Ranya Hezzi, Khemaies Ben Rhouma, Hafedh Abdelmelek, Najet Srairi‐Abid, Mohsen Sakly, Riadh Marrouchi   +8 more
wiley   +1 more source

Anatase-Gentamicin Electrophoretic Coatings on Polyurethane-Modified Titanium: Antibacterial Performance, Biocompatibility, and Drug Delivery. [PDF]

Int J Biomater
Gutiérrez-Mejía FA, Vargas-Coronado RF, Vásquez-López C, Díaz-Ballote L, Huchin-Chan C, Villa-de-la-Torre FE, Arana-Argaez VE, Rosales-Ibáñez R, González-González AM, Cruz-Pérez R, Cauich-Rodríguez JV.   +10 more
europepmc   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source