The use of autologous connective tissue, such as pericardium or peritoneum, combined with controlled tissue treatment, has the potential to result in a more durable heart valve prosthesis than current commercial prostheses. ABSTRACT Introduction Valvular heart disease remains a leading cause of morbidity and mortality. Current biological and mechanical
Marvin Steitz +17 more
wiley +1 more source
Use of a synthetic antimicrobial peptide (PA-13) alone or in combination with reduced gentamicin levels to control <i>Escherichia coli</i> contamination in stored boar semen. [PDF]
Keeratikunakorn K +4 more
europepmc +1 more source
Emerging fungal diseases pose a threat to reptiles globally. Increasing detections of onygenalean fungi, particularly Ophidiomyces ophidiicola, Nannizziopsis spp. and Paranannizziopsis spp. in clinically diseased free‐ranging reptiles, indicate likely ongoing spread within wild reptile populations.
RG Butcher +10 more
wiley +1 more source
Exploring molecular mechanisms of aminoglycoside resistance in Escherichia coli MG1655 using the antibiotic resistance growth plate. [PDF]
Cullen LBL +5 more
europepmc +1 more source
Introduction Antimicrobial resistance (AMR) may lead to increasing inefficacy and treatment failure of bacterial infections in the future. Antimicrobial stewardship (AMS) programmes are critical to ensuring the continued efficacy of available antimicrobials.
JKH Hoong, C Boyd, C Secombe, D Byrne
wiley +1 more source
Synergistic effects of antibiotics and fucoidan on dual-species Staphylococcus aureus and Acinetobacter baumannii biofilm in diabetic rat wound models. [PDF]
Nazari M +4 more
europepmc +1 more source
Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon +3 more
wiley +1 more source
Comparison of Infectious Complications After Transrectal Prostate Biopsy Under Two Antibiotic Prophylaxis Regimens: Ceftriaxone Plus Cefixime Versus Ciprofloxacin Plus Gentamicin. [PDF]
Balık AY +5 more
europepmc +1 more source
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand +8 more
wiley +1 more source
The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis
Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan +17 more
wiley +1 more source

