Results 161 to 170 of about 161,407 (266)

Severe chronic neutrophilic cholangiohepatitis with massive choledocholithiasis and hepatolithiasis in a pony

open access: yesEquine Veterinary Education, EarlyView.
Summary A 20‐year‐old Camargue pony mare was referred for acute‐onset neurological signs and intermittent colic. Clinical examination revealed obtundation, cranial nerve deficits, head pressing, ventral strabismus and ataxia. Laboratory analyses showed marked hyperammonaemia, hyperbilirubinemia, severe increases in liver enzymes, hypoalbuminaemia and ...
C. Maino   +5 more
wiley   +1 more source

MT-RNR1 genotype testing for preventing aminoglycoside-mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx). [PDF]

open access: yesBr J Clin Pharmacol
McDermott JH   +16 more
europepmc   +1 more source

Surgical management of congenital extrahepatic portosystemic shunt in a pony foal

open access: yesEquine Veterinary Education, EarlyView.
Summary A five‐month‐old Welsh pony filly was admitted to the Veterinary Teaching Hospital of the University of Helsinki due to neurological signs. Clinicopathological findings showed elevated ammonium and bile acid levels. Computed tomography revealed an aberrant vessel originating from an enlarged splenic vein, leading to the right azygos vein ...
N. Hakonen   +4 more
wiley   +1 more source

Ectopic pregnancy in a horse

open access: yesEquine Veterinary Education, EarlyView.
Summary An ectopic fetus was discovered in the abdominal cavity of a 21‐year‐old Haflinger mare, which was referred to an equine clinic because of colic symptoms. The mare had been inseminated 3 years previously and was confirmed pregnant at 90 days.
M. S. Swoboda   +3 more
wiley   +1 more source

The trimeric Shu complex in C. elegans is an ATPase that remodels RAD51 filaments in the homologous recombination‐associated DNA damage response

open access: yesThe FEBS Journal, EarlyView.
The C. elegans Shu complex (RFS‐1/RIP‐1/SWS‐1) is a DNA‐dependent ATPase that regulates RAD‐51 filaments during homologous recombination. The trimer preferentially binds 5′‐exposed DNA, remodels RAD‐51 filaments via ATP hydrolysis, and stabilizes filaments through ATP binding.
Sam Siu Hang Chu   +4 more
wiley   +1 more source

Comparison of pharmacogenomic guidance in Australian prescribing resources and international pharmacogenomic guidelines

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Pharmacogenomic‐guided medication management optimises drug therapy to enhance patient outcomes. Despite clinical utility, implementation in Australia remains limited, partly due to the lack of clear and consistent guidance. Aim This study evaluated the presence and consistency of pharmacogenomic testing indication categories and ...
Ruby Soueid   +4 more
wiley   +1 more source

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