Results 141 to 150 of about 1,591 (170)

A Review of the Pharmacology, Toxicity, and Pharmacokinetics of Geraniin

Journal of Biochemical and Molecular Toxicology
ABSTRACT Geraniin, a complex tannin compound, was first extracted from Geranium thunbergii . Since its isolation, it has attracted significant scholarly interest due to its diverse biological activities.
Jiangli Wan, Chunli Fan, Chen Zhang, Lin Li, TingTing Feng   +4 more
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Geraniin Promotes Recovery of Hematopoietic Cells after Radiation Injury

The American Journal of Chinese Medicine, 2017
Cells of the hematopoietic system are uniquely radiosensitive due to their rapid proliferation. Consequently, immune suppression readily and undesirably results from irradiation. Our previous studies demonstrated that geraniin isolated from Nymphaea tetragona var.
So Jin, Bing, Jinhee, Cho, Areum, Kim, Kalahe Hewage Iresha Nadeeka Madushani, Herath, Ginnae, Ahn, Nam Ho, Lee, Jae Woo, Park, Youngheun, Jee   +7 more
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Abstract B173: Inhibition of the Mdm2-p53 interaction by geraniin.

Molecular Cancer Therapeutics, 2011
Abstract Damage by UV, IR, chemical agents and other stresses causes cell cycle arrest and induces DNA repair in eukaryotic cells while severe DNA damage invokes apoptosis. Cell cycle checkpoint signaling pathways are responsible for cell cycle arrest and decisions about cell survival or apoptosis.
Daisuke Tatsuda, Masatomi Iijima, Takashi Kitayama, Isao Momose, Akio Nomoto   +4 more
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Induction of P53 genes in human hepatoma cells by Geraniin

2010 3rd International Conference on Biomedical Engineering and Informatics, 2010
Aim: To study the effect of Geraniin on the expression of P53 genes in human hepatoma HepG2 cells. Methods: Cell survival was measured using MTT metabolic viability assay. Apoptosis of HepG2 was investigated by DNA gel electrophore; The level of P53 gene expression was measured by reverse transcription polymerase chain reaction (RT-PCR) and Western ...
Zhe Xiong Jin, Bao Qing Wang
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Induction of apoptosis in human gastric carcinoma cell by Geraniin

2010 3rd International Conference on Biomedical Engineering and Informatics, 2010
Aim: To study the anti-tumour effect of Geraniin isolated from Agrimonia pilosa ledeb. Methods: MTT was used to study anti-tumor effect of Geraniin in vitro. Morphological observation of the cells was completed by fluorescence microscope. The effect of Gerannin on cell apoptosis in human gastric carcinoma SGC-7901 cells was studied by flow cytometry ...
Bao Qing Wang, Zhe Xiong Jin
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In Vitro BACE1 Inhibitory Activity of Geraniin and Corilagin from Geranium thunbergii

Planta Medica, 2013
Generation of amyloid β peptide through the proteolytic process of amyloid precursor protein by β-secretase and γ-secretase is a main casual factor of Alzheimer's disease, since amyloid β peptide is a major and crucial component of senile plaques in Alzheimer's disease brains.
Kumju, Youn, Mira, Jun
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Geraniin: A dietary ellagitannin as a modulator of signalling pathways in cancer progression

Fitoterapia
Cancer remains a global health challenge, necessitating the exploration of novel therapeutic agents. Current treatment options are unable to overwhelm and cure the cancer burden. Hence, identifying new bioactive molecular entities with potent anticancer activity is the need of the hour.
Naresh Narayanan, Prabakaran, Suvaasni, Prasad, Kiruthigaa, Krishnan, Sivaramakrishnan, Venkatabalasubramanian   +3 more
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An isobolographic analysis of the anti-nociceptive effect of geraniin in combination with morphine or diclofenac

Journal of Basic and Clinical Physiology and Pharmacology, 2017
Abstract Background: Geraniin, a dehydroellagitannin, is a major component of the aqueous extract of the aerial parts of Phyllanthus muellerianus (Kuntze) Exell.
Eric, Boakye-Gyasi, Ella Anle, Kasanga, Elvis Ofori, Ameyaw, Wonder Kofi Mensah, Abotsi, Robert Peter, Biney, Christian, Agyare, Eric, Woode   +6 more
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Geranium thunbergii: In Vitro Culture and the Production of Geraniin and Other Tannins

1995
Geranium (family Geraniaceae) comprises about 400 species and grows in cosmopolitan distribution, chiefly concentrated in temperate regions. Similar to the plants in other genera of Geraniaceae, Pelargonium, Erodium, Monsonia, and Sarcocaulon, Geranium plants such as G. ibericum, G. renardii, G. sanguineum, etc.
K. Ishimaru, K. Shimomura
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Isolation and Characterization of Geraniin and Galloyl-Geraniin fromSpondias mombin

Planta Medica, 1990
J. Corthout, L. Pieters, M. Claeys, A. Vlietinck   +3 more
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