Results 161 to 170 of about 1,020 (190)
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Equilibrated stereostructures of hydrated geraniin and mallotusinic acid
Tetrahedron Letters, 1980Abstract Partial revision of the hydrated structure, and determination of the absolute configurations of geraniin and mallotusinic acid lead to structures I-A and II-A, respectively.
Takuo Okuda +2 more
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2017
Geraniin has been credited with a range of bioactive properties and therefore merits greater research into its potential pharmaceutical, nutraceutical and cosmetic applications. To clarify its functionalities and to explore future applications, a more comprehensive understanding of geraniin; its physiochemical, permeability, bioavailability and ...
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Geraniin has been credited with a range of bioactive properties and therefore merits greater research into its potential pharmaceutical, nutraceutical and cosmetic applications. To clarify its functionalities and to explore future applications, a more comprehensive understanding of geraniin; its physiochemical, permeability, bioavailability and ...
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A Review of the Pharmacology, Toxicity, and Pharmacokinetics of Geraniin
Journal of Biochemical and Molecular ToxicologyABSTRACT Geraniin, a complex tannin compound, was first extracted from Geranium thunbergii . Since its isolation, it has attracted significant scholarly interest due to its diverse biological activities.
Jiangli Wan +4 more
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Abstract B173: Inhibition of the Mdm2-p53 interaction by geraniin.
Molecular Cancer Therapeutics, 2011Abstract Damage by UV, IR, chemical agents and other stresses causes cell cycle arrest and induces DNA repair in eukaryotic cells while severe DNA damage invokes apoptosis. Cell cycle checkpoint signaling pathways are responsible for cell cycle arrest and decisions about cell survival or apoptosis.
Daisuke Tatsuda +4 more
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Induction of P53 genes in human hepatoma cells by Geraniin
2010 3rd International Conference on Biomedical Engineering and Informatics, 2010Aim: To study the effect of Geraniin on the expression of P53 genes in human hepatoma HepG2 cells. Methods: Cell survival was measured using MTT metabolic viability assay. Apoptosis of HepG2 was investigated by DNA gel electrophore; The level of P53 gene expression was measured by reverse transcription polymerase chain reaction (RT-PCR) and Western ...
Zhe Xiong Jin, Bao Qing Wang
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Induction of apoptosis in human gastric carcinoma cell by Geraniin
2010 3rd International Conference on Biomedical Engineering and Informatics, 2010Aim: To study the anti-tumour effect of Geraniin isolated from Agrimonia pilosa ledeb. Methods: MTT was used to study anti-tumor effect of Geraniin in vitro. Morphological observation of the cells was completed by fluorescence microscope. The effect of Gerannin on cell apoptosis in human gastric carcinoma SGC-7901 cells was studied by flow cytometry ...
Bao Qing Wang, Zhe Xiong Jin
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Geraniin: A dietary ellagitannin as a modulator of signalling pathways in cancer progression
FitoterapiaCancer remains a global health challenge, necessitating the exploration of novel therapeutic agents. Current treatment options are unable to overwhelm and cure the cancer burden. Hence, identifying new bioactive molecular entities with potent anticancer activity is the need of the hour.
Naresh Narayanan, Prabakaran +3 more
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In Vitro BACE1 Inhibitory Activity of Geraniin and Corilagin from Geranium thunbergii
Planta Medica, 2013Generation of amyloid β peptide through the proteolytic process of amyloid precursor protein by β-secretase and γ-secretase is a main casual factor of Alzheimer's disease, since amyloid β peptide is a major and crucial component of senile plaques in Alzheimer's disease brains.
Kumju, Youn, Mira, Jun
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Isolation and Characterization of Geraniin and Galloyl-Geraniin fromSpondias mombin
Planta Medica, 1990J. Corthout +3 more
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Geranium thunbergii: In Vitro Culture and the Production of Geraniin and Other Tannins
1995Geranium (family Geraniaceae) comprises about 400 species and grows in cosmopolitan distribution, chiefly concentrated in temperate regions. Similar to the plants in other genera of Geraniaceae, Pelargonium, Erodium, Monsonia, and Sarcocaulon, Geranium plants such as G. ibericum, G. renardii, G. sanguineum, etc.
K. Ishimaru, K. Shimomura
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