Results 121 to 130 of about 24,196 (383)

Erectile Dysfunction in Germ Cell Tumor Survivors

The World Journal of Men's Health, 2021
Purpose: Germ cell tumors (GCTs) are the most common malignant neoplasms in adolescents and young adults, and most patients with these tumors can be completely cured. Therefore, maintaining quality of life (QOL) is important.
Koichi Okada, Kazutoshi Fujita, Shinichiro Fukuhara, Hiroshi Kiuchi, Motohide Uemura, Ryoichi Imamura, Norio Nonomura   +6 more
doaj   +1 more source

Isolated eyeball metastasis of non-seminomatous germ cell testicular tumor [PDF]

, 2011
Introduction. Testicular tumors most frequently metastasize to regional lymph nodes. Non-seminomatous tumor metastasis of testicle (NSGCTT) to the eyeball is rare. Case report.
Bojanić Nebojša, Janičić Aleksandar, Mićić Sava, Nale Đorđe, Vuković Ivan, Vuksanović Aleksandar   +5 more
core   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

Treatment of pediatric intracranial germ cell tumors: Tiantan experience

Chinese Journal of Contemporary Neurology and Neurosurgery
Pediatric intracranial germ cell tumors (GCT) are clinically rare but highly heterogeneous tumors, primarily occurring in children and adolescents. The treatment method depends on the tumor type.
LI Xiang, LU Li-juan, GONG Jian
doaj   +1 more source

Transient increases in intracellular calcium and reactive oxygen species levels in TCam-2 cells exposed to microgravity [PDF]

, 2017
The effects of microgravity on functions of the human body are well described, including alterations in the male and female reproductive systems. In the present study, TCam-2 cells, which are considered a good model of mitotically active male germ cells,
Catizone, A, Guarnieri, S, Mariggiò, M. A., Morabito, C, Ricci, G, Schiraldi, C   +5 more
core   +2 more sources

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Salvage resection of advanced mediastinal tumors [PDF]

, 2019
The surgical treatment of locally advanced mediastinal tumors invading the great vessels and other nearby structures still represent a tricky question, principally due to the technical complexity of the resective phase, the contingent need to carry out
Andreetti, Claudio, Ciccone, Anna Maria, D’Andrilli, Antonio, Ibrahim, Mohsen, Maurizi, Giulio, Menna, Cecilia, Poggi, Camilla, Rendina, Erino Angelo, Vanni, Camilla, Venuta, Federico   +9 more
core   +1 more source

Genome‐Wide Association Analyses Reveal the Genetic Basis of EMS Mutagenesis Efficiency in Rice

Advanced Science, EarlyView.
Based on large‐scale screening of 420 rice accessions, GWAS identified the Rc locus as a key regulator of EMS mutagenesis efficiency. Functional Rc alleles enhance both seed survival and genome‐wide mutation frequency by boosting antioxidant enzyme activities (CAT, SOD, POD) and reducing oxidative damage.
Peizhou Xu, Qinglu Zhang, Le Xue, Zhen Zhang, Nanhui Luo, Zhaoyang Cheng, Duo Xia, Shuqin Zheng, Xianjun Wu, Hao Zhou   +9 more
wiley   +1 more source

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

Hepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo, Ivana Nikolic, Alfonso Mora, Elena Rodríguez, Luis Leiva‐Vega, Aránzazu Pintor‐Chocano, Daniel Horrillo, Lourdes Hernández‐Cosido, Jorge L. Torres, Eva Novoa, Rubén Nogueiras, Gema Medina‐Gómez, Miguel Marcos, Magdalena Leiva, Guadalupe Sabio   +14 more
wiley   +1 more source

Genome-wide methylation analysis identifies genes silenced in non-seminoma cell lines [PDF]

, 2016
Silencing of genes by DNA methylation is a common phenomenon in many types of cancer. However, the genome wide effect of DNA methylation on gene expression has been analysed in relatively few cancers.
A Meissner, A Sadakierska-Chudy, A Watanabe, AP Feinberg, AP Feinberg, BB Maymon, C Stirzaker, C Tan, D Aran, D Nettersheim, DJ Smiraglia, DJ Weisenberger, E Magnusdottir, E Magnusdottir, E Ruark, F Nakaki, G Nagamatsu, GJ Netto, H Heyn, H Noushmehr, H Wermann, J Beyer, J de Jong, J Zhou, JE Korkola, JF Amatruda, JM Teodoridis, JN Jeyapalan, K Takahashi, K Terashima, L Shen, LH Looijenga, M Kulis, M Matsutani, M Toyota, M Yamaji, MA Rijlaarsdam, MG Mathieu, MJ Murray, MR Estecio, MT Bocker, MW Pfaffl, N Grabole, N Okashita, NY Chia, PW Andrews, R Behr, R Behr, R Lister, R Lowe, RA Irizarry, RA Irizarry, RD Palmer, RJ Motzer, RR Pandey, S Roach, T Ueki, V Hovestadt, Y Mizuno, YG van der Zwan, Z Ma   +60 more
core   +2 more sources