The developing bone was identified as an M2a‐like macrophage driven immune microenvironment with multidimensional developmental signatures. hME‐ApoEVs were successfully fabricated via stimulating the M2a‐like developing microenvironment in vitro and confirmed its recapitulation of developmental features.
Xiaoran Yu +11 more
wiley +1 more source
Unveiling embryonal carcinoma: a rare clinico-pathological entity. [PDF]
Bhaidkar K, Sawarkar P.
europepmc +1 more source
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
First Case of Neuroblastoma-Like Somatic-Type Malignancy Arising in the Teratomatous Component of a Mixed Non-Seminomatous Testicular Germ Cell Tumor in an Adult. [PDF]
Ziade K +4 more
europepmc +1 more source
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos +8 more
wiley +1 more source
Talin1 is downregulated in testicular germ cell tumors according to combined bioinformatics and experimental approaches. [PDF]
Razmi M +7 more
europepmc +1 more source
ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius +2 more
wiley +1 more source
Molecular pathology of testicular germ cell tumours: an update for practicing pathologists. [PDF]
Fichtner A +3 more
europepmc +1 more source
The barley–malt–beer chain: A process and food safety approach
Abstract This review addresses the current state of knowledge on the barley–malt–beer chain and its main physical, chemical, and microbiological contaminants, with particular emphasis on spoilage microorganisms and their toxic metabolites. The barley–malt–beer production chain represents a mature and globally relevant agro‐industrial sector that ...
José Gómez‐Espinoza +5 more
wiley +1 more source
Soybean seed coat properties as determinants of natto and sprout quality
Abstract BACKGROUND Improving breeding efficiency for superior soybean (Glycine max (L.) Merr.) germplasm used in natto and sprouts requires understanding how seed coat properties relate to quality and functional traits. METHODS We measured seed weight, water uptake, and sprout length and thickness across various genotypes tested at different locations
Mehri Hadinezhad +4 more
wiley +1 more source

