Results 71 to 80 of about 414,793 (308)
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Production of live fish derived from frozen germ cells via germ cell transplantation
Stem Cell Research, 2018 The conservation of endangered fish is an urgent issue. Although cryo-banking of fish gametes might ultimately help conserve endangered fish, cryopreservation of fish eggs or embryos is still not possible due to their large size and high yolk content ...
Goro Yoshizaki, Seungki Lee
doaj +1 more source
Developmental changes in the histological structure of the testes, and testosterone profiles in male guinea fowls (Numida meleagris) [PDF]
, 2017 Owing to the paucity of information on the reproductive biology of guinea fowls, a study involving a total of 66 males was conducted, and documented the developmental changes in histological structure of the testes of guinea cocks from hatching until ...
Abdul-Rahman, Iddriss I. +2 more
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Actomyosin-mediated apical constriction promotes physiological germ cell death in C. elegans.
PLoS BiologyGerm cell apoptosis in Caenorhabditis elegans hermaphrodites is a physiological process eliminating around 60% of all cells in meiotic prophase to maintain tissue homeostasis. In contrast to programmed cell death in the C.
Tea Kohlbrenner +6 more
doaj +1 more source
Primordial Germ Cell Specification and Migration [version 1; referees: 3 approved]
F1000Research, 2015 Primordial germ cells are the progenitor cells that give rise to the gametes. In some animals, the germline is induced by zygotic transcription factors, whereas in others, primordial germ cell specification occurs via inheritance of maternally provided ...
Florence Marlow
doaj +1 more source
Primordial follicular assembly in humans : revisited [PDF]
, 2009 Peer ...
A. Maheshwari +8 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2018 Germ cell research in vertebrates has traditionally been challenging, but recent breakthroughs have overcome technical difficulties, demonstrating and expanding the power of the zebrafish experimental system for their analysis in vivo. Exploiting the transparency of the zebrafish embryo, germ cell migration was the first topic that moved the germ cells
Roland Dosch, Roland Dosch
openaire +4 more sources
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
The ligand binding domain of GCNF is not required for repression of pluripotency genes in mouse fetal ovarian germ cells. [PDF]
PLoS ONE, 2013 In mice, successful development and reproduction require that all cells, including germ cells, transition from a pluripotent to a differentiated state. This transition is associated with silencing of the pluripotency genes Oct4 and Nanog.
Leah M Okumura +2 more
doaj +1 more source