Clearance of germ granules in the soma [PDF]
F1000 Biology Reports, 2009 Germ granules are ribonucleoprotein complexes specifically segregated into germ cell lineages in diverse organisms. Recent studies indicate that multiple mechanisms are involved in the clearance of germ granules and their components in somatic cells in Caenorhabditis elegans embryos.
openaire +2 more sources
Vitrification of human immature oocytes before and after in vitro maturation: a review [PDF]
, 2017 The use of immature oocytes subjected to in vitro maturation (IVM) opens interesting perspectives for fertility preservation where ovarian reserves are damaged by pathologies or therapies, as in PCO/PCOS and cancer patients. Human oocyte cryopreservation
Ashourzadeh, S +5 more
core +1 more source
El sistema reproductor femenino de Zearaja chilensis (Guichenot, 1848) (Chondrichthyes, Rajidae): Gametogénesis y validación microscópica de los criterios de madurez [PDF]
, 2015 Los condrictios son extremadamente susceptibles a la explotación pesquera debido, entre otras cosas, a sus adaptaciones reproductivas. Los conocimientos básicos de sus parámetros reproductivos son esenciales, ya sea desde el punto de vista ecológico como
Di Giacomo, Edgardo Ernesto +2 more
core +1 more source
Protein-based condensation mechanisms drive the assembly of RNA-rich P granules
eLife, 2021 Germ granules are protein-RNA condensates that segregate with the embryonic germline. In Caenorhabditis elegans embryos, germ (P) granule assembly requires MEG-3, an intrinsically disordered protein that forms RNA-rich condensates on the surface of PGL ...
Helen Schmidt +3 more
doaj +1 more source
Germ Granule Evolution Provides Mechanistic Insight into Drosophila Germline Development
Molecular Biology and Evolution, 2023 Abstract The copackaging of mRNAs into biomolecular condensates called germ granules is a conserved strategy to posttranscriptionally regulate germline mRNAs. In Drosophila melanogaster, mRNAs accumulate in germ granules by forming homotypic clusters, aggregates containing multiple transcripts from the same gene. Nucleated by Oskar (Osk),
Dominique A Doyle +11 more
openaire +2 more sources
Unidirectional P-body transport during the yeast cell cycle. [PDF]
PLoS ONE, 2014 P-bodies belong to a large family of RNA granules that are associated with post-transcriptional gene regulation, conserved from yeast to mammals, and influence biological processes ranging from germ cell development to neuronal plasticity.
Cecilia Garmendia-Torres +9 more
doaj +1 more source
A single transcription factor is sufficient to induce and maintain secretory cell architecture [PDF]
, 2017 We hypothesized that basic helix–loop–helix (bHLH) MIST1 (BHLHA15) is a “scaling factor” that universally establishes secretory morphology in cells that perform regulated secretion.
Blanc, Valerie +12 more
core +2 more sources
Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness. [PDF]
, 2020 Antibody-mediated immune responses rely on antigen recognition by the B cell antigen receptor (BCR) and the proper engagement of its intracellular signal effector proteins.
Becker, S. +10 more
core +2 more sources
DLC-1 facilitates germ granule assembly in Caenorhabditis elegans embryo
Molecular Biology of the Cell, 2022 Interactions between DLC-1/LC8 family protein and several germ granule components suggest a role for DLC-1 in promoting phase separation of non-membrane bound cellular organelles. This function of DLC-1 was genetically validated and was independent of dynein motor or cell polarity.
Day, Nicholas J. +3 more
openaire +2 more sources
A new species of Daldinia (Xylariaceae) from the Argentine subtropical montane forest [PDF]
, 2016 Based on a combination of morphological, molecular phylogenetic and chemotaxonomic evidence, a new species of Daldinia from Northwest of Argentina is described. Daldinia korfii is morphologically related to D.
Hladki, Adriana Ines +5 more
core +1 more source