Results 91 to 100 of about 4,224,412 (338)
Studies on Germinal Center Biology [PDF]
, 2017 The germinal center reaction is at the heart of the humoral immune response; it comprises one major arm of the immune system, with the other arm being the cellular response. It is the site where B cells undergo somatic hyper-mutation, class switching,
Sarmiento, Selina
core
Cell Reports, 2022 Summary: A main feature of Wiskott-Aldrich syndrome (WAS) is increased susceptibility to autoimmunity. A key contribution of B cells to development of these complications has been demonstrated through studies of samples from affected individuals and ...
Marc Descatoire +8 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior +11 more
wiley +1 more source
mBioGammaherpesviruses are ubiquitous pathogens that establish lifelong infection and are associated with the development of cancer and multiple sclerosis.
Erika R. Johansen +5 more
doaj +1 more source
A mechanism of T cell dependent selection of antigen engaged Germinal Center B cells. [PDF]
PLoS ONE, 2018 A model of B cell affinity selection is proposed, and an explanation of peripheral tolerance mechanisms through antibody repertoire editing is presented.
Vinod Krishna, Kurtis E Bachman
doaj +1 more source
Compartments and Connections Within the Germinal Center
Frontiers in Immunology, 2021 Protective high affinity antibody responses emerge through an orchestrated developmental process that occurs in germinal centers (GCs). While GCs have been appreciated since 1930, a wealth of recent progress provides new insights into the molecular and ...
Domenick E. Kennedy, Marcus R. Clark
doaj +1 more source
A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho +7 more
wiley +1 more source
Follicular lymphomas of germinal center (B- or T-cell) origin [PDF]
, 2018 Follicular lymphomas of germinal center (B- or T-cell) origin include follicular lymphoma (FL), nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), and angioimmunoblastic T-cell lymphoma (AITL).Other lymphomas of presumed follicular origin comprise ...
Gloghini, Annunziata, Carbone, Antonino
core +1 more source
Diagnostic Pathology, 2011 Background Recently, human germinal center-associated lymphoma (HGAL) gene protein has been proposed as an adjunctive follicular marker to CD10 and BCL6. Methods Our aim was to evaluate immunoreactivity for HGAL in 82 cases of follicular lymphomas (FLs) -
Rubini Corrado +7 more
doaj +1 more source
Spontaneous germinal centers and autoimmunity [PDF]
Autoimmunity, 2017 Germinal centers (GCs) are dynamic microenvironments that form in the secondary lymphoid organs and generate somatically mutated high-affinity antibodies necessary to establish an effective humoral immune response. Tight regulation of GC responses is critical for maintaining self-tolerance.
Phillip P. Domeier +2 more
openaire +3 more sources