Results 81 to 90 of about 72,003 (345)
VMP001-NP immunization triggers germinal center formation.
, 2013 (A) C57Bl/6 mice were vaccinated with 0.1 µg VMP001 and 5 µg MPLA in either soluble or VMP001-NP formulations, and on day 21, inguinal dLNs were isolated and analyzed for germinal center formation.
Darrell J. Irvine (333609) +5 more
core +1 more source
Haematologica, 2013 Diffuse large B-cell lymphoma can be classified by gene expression profiling into germinal center and activated B-cell subtypes with different prognoses after rituximab-CHOP.
Carlo Visco +35 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Transcriptional Regulation of Germinal Center Formation
Frontiers in Immunology, 2018 Germinal centers (GCs) are essential structures of the humoral immune response, which form in the periphery in response to T cell dependent antigens. During the GC reaction, B cells undergo critical differentiation steps, which ultimately lead to the ...
Shuang Song +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A mathematical model for germinal centre kinetics and affinity maturation
, 2002 We present a mathematical model which reproduces experimental data on the germinal centre (GC) kinetics of the primed primary immune response and on affinity maturation observed during the reaction.
DAGMAR IBER +6 more
core +1 more source
Selenium saves ferroptotic TFH cells to fortify the germinal center
, 2021 Inhibition of ferroptosis via selenium supplementation promotes the survival of follicular helper T cells, boosting the germinal center and antibody response following vaccination in mice and ...
Denton, Alice E, Linterman, Michelle A
core +1 more source
Non‐germinal center B‐cell subtype of pediatric diffuse large B‐cell lymphoma in Japan: A retrospective cohort study [PDF]
, 2023 Daiki Hori +7 more
openalex +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source