Results 21 to 30 of about 72,003 (345)
B Cell Responses to a Peptide Epitope. VII. Antigen-Dependent Modulation of the Germinal Center Reaction [PDF]
, 1998 Germinal center responses to two analogous peptides, PS1CT3 and G32CT3, that differ in sequence only at one position within the B cell epitopic region were examined.
Anshu Agarwal +2 more
core +4 more sources
Annual Review of Immunology, 2012 Germinal centers (GCs) were described more than 125 years ago as compartments within secondary lymphoid organs that contained mitotic cells. Since then, it has become clear that this structure is the site of B cell clonal expansion, somatic hypermutation, and affinity-based selection, the combination of which results in the production of high-affinity ...
Gabriel D, Victora +1 more
openaire +4 more sources
Frontiers in Immunology, 2022 The development of a safe and effective vaccine against Yersinia pestis, the causative organism for plague disease, remains an important global health priority.
Darrell R. Galloway +8 more
doaj +1 more source
Antibody Mediated Intercommunication of Germinal Centers
Cells, 2022 Antibody diversification and selection of B cells occur in dynamic structures called germinal centers (GCs). Passively administered soluble antibodies regulate the GC response by masking the antigen displayed on follicular dendritic cells (FDCs).
Theinmozhi Arulraj +2 more
doaj +1 more source
Analysis of immunophenotypic features in hyaline vascular type Castleman disease
Diagnostic Pathology, 2023 Background Studies suggested that the immunophenotype of hyaline vascular type Castleman disease (HVCD) lacked characteristics, which was easy to be confused with other diseases. Methods From January 2010 to June 2022, 17 cases of HVCD were selected from
Yu Chang, Yu Ma, Chen Chang, Wensheng Li
doaj +1 more source
Tinigible Body Macrophages in Regulation of Germinal Center Reactions [PDF]
, 1997 Tingible body macrophages (TBM), long thought simply as scavengers of apoptotic lymphocytes, are located in the unique microenvironment of germinal centers in close proximity to antigen-retaining follicular dendritic cells (FDC).
John P. Smith +3 more
openalex +3 more sources
Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells
Viruses, 2022 Tissue and subcellular localization and its changes upon cell activation of virus-restricting APOBEC3 at protein levels are important to understanding physiological functions of this cytidine deaminase, but have not been thoroughly analyzed in vivo.
Shota Tsukimoto +8 more
doaj +1 more source
Deriving a germinal center lymphocyte migration model from two-photon data [PDF]
, 2008 Recently, two-photon imaging has allowed intravital tracking of lymphocyte migration and cellular interactions during germinal center (GC) reactions. The implications of two-photon measurements obtained by several investigators are currently the subject ...
Michael Meyer-Hermann +16 more
core +1 more source
Th17 effector cells support B bell responses outside of germinal centres [PDF]
, 2012 Th17 cells are pro-inflammatory CD4+T cells, which are important in immune responses against fungal pathogens and extracellular bacteria and have also been implicated in various autoimmune syndromes.
David R Withers +39 more
core +1 more source
Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers. [PDF]
PLoS ONE, 2013 Lymphoid tissue immunopathology is a characteristic feature of chronic HIV/SIV infection in AIDS-susceptible species, but is absent in SIV-infected natural hosts.
Amanda J Martinot +9 more
doaj +1 more source