Results 111 to 120 of about 289,899 (373)
Advanced Science, EarlyView.This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
Beyond Gender Differences in U.S. Life Cycle Happiness [PDF]
An integration of methods and theories from economics, psychology, sociology and gerontology offers a more useful means for understanding gender differences in life-cycle happiness.
Enrico A. Macelli, Richard A. Easterlin
core
Advanced Science, EarlyView.Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang +9 more
wiley +1 more source
Polyphenol Concentrate from Kazakhstan Cabernet Sauvignon Collection of Grapes
Central Asian Journal of Global Health, 2014 Introduction. Nowadays, most of the research in the field of gerontology is focused on the effects of the grape polyphenols. In particular, resveratrol has been shown to increase life expectancy of various living organisms, including mammals. Resveratrol
Zarina Shulgau +4 more
doaj +1 more source
Natural Landscape and Environmental Gerontology [PDF]
, 2018 Diego Sánchez González
openalex +1 more source
Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription
Advanced Science, EarlyView.This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen +14 more
wiley +1 more source
Ten years of integrated care for the older in France
International Journal of Integrated Care, 2011 Background: This paper analyzes progress made toward the integration of the French health care system for the older and chronically ill population. Policies: Over the last ten years, the French health care system has been principally influenced by two ...
Dominique Somme, Matthieu de Stampa
doaj +1 more source
Advanced Science, EarlyView.This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang +12 more
wiley +1 more source
Excluded from the Good Life? An Ethical Approach to Conceptions of Active Ageing
Social Inclusion, 2019 Contesting previous deficit-oriented models of ageing by focusing on the resources and potential of older people, concepts of ‘successful’, ‘productive’, and ‘active ageing’ permeate social policy discourses and agendas in ageing societies. They not only
Larissa Pfaller, Mark Schweda
doaj +1 more source
EXPLORING DEI IN A GLOBAL PERSPECTIVE: AGHE INSIGHTS INTO OUR WORK SUPPORTING GERONTOLOGY AND GERIATRIC EDUCATORS [PDF]
, 2022 Dana Burr Bradley, Judith L. Howe
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