Results 111 to 120 of about 246,242 (358)

“On Ageing and Old Age. Basic Problems and Historic Aspects of Gerontology and Geriatrics”. M. D. Grmek. Monographie Biological, vol. v. No. 2. 18 December 1958. [PDF]

, 1959
Edwin Clarke
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Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

Advanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves, Darius Lane, Adam Wahida, Md. Jakaria, Pawel Kalinowski, Adam Southon, Abdel Ali Belaidi, Teresa Samperi‐Esteve, Triet Phu Minh Nguyen, Peng Lei, Marcus Krueger, Stefan Mueller, Marcus Conrad, Puja Agarwal, Sue E Leurgans, Julie Schneider, Ashley I. Bush, Scott Ayton   +17 more
wiley   +1 more source

Second International Gerontological Congress [PDF]

, 1951

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AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Higher Education Institutions as Strategic Centers for Promoting Social Innovation in Gerontology: Insights from the Senior Innovation Lab Training Initiative

Geriatrics
Background: Social innovation and gerontology develop a wide range of actions aimed at supporting and improving the needs of long-lived populations. Higher education institutions (HEIs) are drivers of change, and their potential to develop solutions ...
Susana Feijóo-Quintas, Noelia Gerbaudo-González, Manuel Gandoy-Crego, Mª del Carmen Gutiérrez-Moar, Elísio Costa, David Facal   +5 more
doaj   +1 more source

A Longitudinal Study Reveals Metabolomic Markers for Individuals at Risk, Disease Severity, and Treatment Response in Rheumatoid Arthritis

Advanced Science, EarlyView.
This study investigates plasma metabolomic biomarkers for rheumatoid arthritis (RA) development using longitudinal data from 209 RA patients and 56 individuals at risk. It also reveals metabolic signatures linked to severity, age, sex, and anti‐citrullinated protein autoantibody in RA.
Chenxi Zhu, Jiayi Xu, Siyu He, Qian Niu, Yi Liu, Xin Guo, Huifang Hu, Rui Sun, Tao Chen, Yan Liu, Zhiqiang Xu, Na Jiang, Lipu Yao, Lunzhi Dai, Qinghua Zou, Fanxin Zeng, Liesu Meng, Inger Gjertsson, Rikard Holmdahl, Bin Yang, Dan Du, Yi Zhao   +21 more
wiley   +1 more source

Pedagogical Innovation with Sense? A Seminal Experiment of Service-Learning in Gerontological Social Work

Trends in Higher Education
Higher education institutions have been investing in teachers’ professional development and pedagogical innovation, on the one hand, aiming to promote the quality of institutions and, on the other hand, aiming to promote students’ personal and academic ...
Catarina Vieira da Silva, Armanda Gonçalves, Simone Petrella, Paulo C. Dias   +3 more
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Acute pancreatitis in two patients with Parkinson’s disease

Cogent Medicine, 2017
Parkinson’s disease represents one of the most common chronic neurodegenerative diseases in the elderly caused by a reduction of dopamine levels in the brain.
Sanja Kovacic, Sinisa Roginic, Johann Nemrava, Ksenija Gospocic, Maida Seferovic Saric, Kresimir Luetic   +5 more
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Gerontology, A Book of Readings [PDF]

, 1963

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Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

Advanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan, Guo Li, Yanji Chu, Junbo Zhang, Li Yang, Yujin Zhang, Fangfen Liu, Jiayun Li, Mengting Chen, Ben Wang, Zhixiang Zhao, Wei Shi, Yiya Zhang, Guangtong Deng, Xinwei Kuang, Hongfu Xie, Yufan Cheng, Zhili Deng, Ji Li, Yan Tang   +19 more
wiley   +1 more source