Results 121 to 130 of about 249,502 (408)
Advanced Science, EarlyView.The N‐acetyltransferase‐10 (NAT10)‐mediated mRNA N4‐acetylcytidine modification enhances the stability of CXCL2 and KLF5 mRNA. Then, secreted CXCL2 promotes M2 macrophage polarization and oncostatin M secretion, activating NAT10 expression via STAT3 signaling.
Chen Chen +17 more
wiley +1 more source
SCARF: A Biomedical Association Rule Finding Webserver [PDF]
arXiv, 2017 The analysis of enormous datasets with missing data entries is a standard task in biological and medical data processing. Large-scale, multi-institution clinical studies are the typical examples of such datasets. These sets make possible the search for multi-parametric relations since from the plenty of the data one is likely to find a satisfying ...
arxiv
The social context of substance use among older adults: Implications for nursing practice
Nursing Open, 2019 Aim The purposes of this paper are (a) to critically analyse the social context of substance use among older adults and (b) to offer strategies for nurses and other health care providers to support the health of older adults experiencing problematic ...
Manpreet Kaur Gill Thandi +1 more
doaj +1 more source
GMS Medizin – Bibliothek – Information, 2016 In 2013 the Public Library of Graz launched a home library service which is unique in Austria up to today: volunteer book messengers visit senior and homebound citizens at their homes.
Burkert, Petra
doaj +1 more source
Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis
Advanced Science, EarlyView.Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao +15 more
wiley +1 more source
Gerontology Newsletter, September 2011 [PDF]
, 2011 Inside this issue: -- Rural Aging Conference-- Congratulations Graduates-- Webiner-- New Website-- Recent Cuts to the State Budgethttps://scholarworks.uni.edu/geronnews/1000/thumbnail ...
University of Northern Iowa. Gerontology Program.
core +1 more source
Advanced Science, EarlyView.Using integrative multi‐omics analyses, this study maps FIIN‐2's targets and signaling networks in liver cancer cells, and identifies covalent AMPKα1 binding as a novel autophagy‐activating mechanism. The findings resolve both on‐target FGFR inhibition and off‐target protein engagement, providing a molecular roadmap to refine covalent kinase inhibitors
Ying Fu +9 more
wiley +1 more source
Gerontology Theory Communicated in the Primary Grades through Picture Books [PDF]
, 2018 Educational Objectives 1. To recognize children’s first literature as a means of socialization to aging and older people. 2. To identify children’s books that reflect basic principles of gerontology theory. 3.
Ansello, Edward F.
core +1 more source
ADAR1‐HNRNPL‐Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease
Advanced Science, EarlyView.ADAR1‐HNRNPL interaction‐repressed circCANX recruits P53 mRNA and UPF1 to assemble a complex in nuclear. This complex promotes P53 mRNA degradation through the NMD pathway, and finally reduces autophagy and stress granules formation to further regulate inflammation.
Ting‐Ting Chen +10 more
wiley +1 more source
Gerontology in and out of Africa [PDF]
, 1997 Some of the most exciting new gerontology globally is coming out of Africa. African gerontology has reached a stage in its development to earn it a respected and unique place in the global ageing arena.
Ferreira, Monica
core +2 more sources