Results 81 to 90 of about 263,699 (331)
Advanced Science, EarlyView.This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng +15 more
wiley +1 more source
Female gerontology in TV-advertising [PDF]
Социологический журнал, 2012 The paper backgrounds the necessity of theoretical advancing the female gerontology project. Two models of female gerontology problems interpretation are considered: the model of “mail dominance” and the model of “female narcissism”.
doaj
Simulation of Demographic Change in Palestinian Territories [PDF]
, 2007 Mortality, birth rates and retirement play a major role in demographic changes. In most cases, mortality rates decreased in the past century without noticeable decrease in fertility rates, this leads to a significant increase in population growth.
A. H. El-ASTAL +4 more
core +2 more sources
Advanced Science, EarlyView.This study mainly combines spatial/single‐cell transcriptomics and metabolomics to reveal LOX+ Malig‐5 as NSCLC brain metastasis‐initiating cells, forming a niche with NET‐releasing neutrophils via the NET‐KRT10 axis. The metastatic niche is involved with metabolic reprogramming, with palmitic acid serving as a key metabolite.
Bo Chen +17 more
wiley +1 more source
Journal of Multidisciplinary HealthcareYuqian Gao,1,* Tianli Li,2,* Xiaohong Mu,1,* Xiaoxia Ren,1 Jing Wang,1 Jiasai Fan,1 Haiyan Zhu,1,3 Xian Wang1,3 1Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 2National ...
Gao Y +7 more
doaj
The Effect of an Aging Suit on Young and Middle-Aged Adults’ Attitudes Toward Older Adults [PDF]
, 2018 Background: Ageism, a type of discrimination based on a person’s age, can lead to negative attitudes, intolerance, and judgment towards older adults. With the increase of older adults in society, understanding the correlates of negative attitudes becomes
Allen, Kelly
core +2 more sources
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Advanced Science, EarlyView.Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
An Education in the Scope and Depth of Gerontological Scholarship [PDF]
, 2023 Joseph E. Gaugler
openalex +1 more source
Raising the level of medical gerontology: Evaluation of the European Academy for Medicine of Ageing course [PDF]
, 2018 The two-year EAMA course was established in 1995 by the Group of European Professors in Medical Gerontology (GEPMG) with the aim of raising the global standard of medical gerontology in (chiefly) European junior faculties. To determine the impact of this
Michel, J-P
core
Advanced Science, EarlyView.IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang +15 more
wiley +1 more source