Results 101 to 110 of about 22,382 (200)
Heterozygous GHR gene mutation in a child with idiopathic short stature [PDF]
Several monogenic defects have been reported to be associated with idiopathic short stature. Focusing on growth hormone receptor (GHR)-gene alterations, the heterozygosity of the same gene defect may be associated with a range of growth deficits.
Pagani, Sara +6 more
core
Global disruption of the GH receptor in mice (GHR-/-) produces a large and reproducible extension in lifespan. Since lack of GH action in muscle resulting in improved glucose homeostasis is potentially a mechanism by which GHR-/- mice are long-lived, and
Berryman, Darlene E. +4 more
core +1 more source
Effect of GH treatment on GHR expression and proliferation of DHD and RH cells.
(A) Expression of the receptor (GHR) in DHD and RH cell lines. Data are mean ± standard deviation of the cell line cultures. GHR mRNA levels were determined by a reverse-transcription polymerase chain reaction.
Maria Tabernero (5666200) +7 more
core +1 more source
Ghr-miR482d trigged production of phased secondary small RNAs in Gorai.011G075600.
A) Schematic diagram of Gorai.011G075600. Grey boxes represent exons. The red bar represents the location of the P-loop of the NBS domain. B) Distribution pattern of small RNAs generated from the region immediately after the P-loop, which was cleaved by ...
Iain Wilson (430308) +5 more
core +1 more source
GH is generally believed to signal exclusively through Janus tyrosine kinases (JAK), particularly JAK2, leading to activation of signal transducers and activators of transcription (STAT), ERK and phosphatidylinositol 3-kinase pathways, resulting in ...
Ishikawa, Mayumi +9 more
core +1 more source
The cDNA of growth hormone receptor (GHR) was cloned from the liver of 2-year common carp (Cyprinus carpio L.) by reverse transcription-polymerase chain reaction (RT-PCR) and rapid amplification of cDNA end (RACE).
Zhu Zuoyan +5 more
core

