Results 81 to 90 of about 22,382 (200)

SOCS2 targets the GHR for proteasomal degradation.

, 2013
(A) Cells were transfected with GHR and Elongin B/C alone or in concert with FLAG-SOCS2. C denotes the control which was transfected with FLAG-SOCS2 and Elongin B/C.
Michael Lund Nielsen (172389), Gunnar Norstedt (31951), Torbjörn Persson (343004), Benedikt M. Kessler (216861), Mattias Vesterlund (343003), Fahad Zadjali (333950), Amilcar Flores-Morales (164259)   +6 more
core   +1 more source

Molecular Design Strategies for High‐Voltage Organic Cathodes

Advanced Energy Materials, Volume 16, Issue 34, 9 September 2026.
This work proposes molecular engineering strategies for high‐voltage organic cathode materials for Li‐ion batteries: (1) increase Li‐O coordination number (CN), (2) achieve a greater increase in aromaticity upon reduction (∆Aromaticity), and (3) add an electron‐withdrawing group (EWG), through a combined experimental and computational study on reported
Sungil Hong, Alae Eddine Lakraychi, Artur Lyssenko, Abhishek Ashwin Panchal, Harshan Reddy Gopidi, Pieremanuele Canepa, Rafael Gómez‐Bombarelli, Yan Yao, Rajeev Surendran Assary   +8 more
wiley   +1 more source

Activation of GH signaling and GH-independent stimulation of growth in zebrafish by introduction of a constitutively activated GHR construct

, 2011
Growth hormone (GH) gene transfer can markedly increase growth in transgenic fish. In the present study we have developed a transcriptional assay to evaluate GH-signal activation (GHSA) in zebrafish embryos.
Pang, Shao-Chen, He, Mu-Dan, Xiong, Feng, Sun, Yong-Hua, Sun, YH, Chinese Acad Sci, State Key Lab Freshwater Ecol & Biotechnol, Inst Hydrobiol, Wuhan 430072, Hubei, Peoples R China, Waters, Michael J., Zhu, Zuo-Yan, sunyonghua@gmail.com, Ahmed, A. S. Ishtiaq   +8 more
core  

GH induces Jak2 release from GHR.

, 2013
Hek293-TR stable cell lines expressing GHR-Rluc and YFP-Jak2 (wt or Y119E) were seeded 24 h before the measurements; doxycycline was added in order to stimulate the expression of YFP-Jak2 constructs.
Peter van Kerkhof (356257), Ana Gracanin (356259), Joyce Putters (356255), Ana C. da Silva Almeida (356256), Ger J. Strous (299053), Agnes G. S. H. van Rossum (356258)   +5 more
core   +1 more source

Loss of Adipose Growth Hormone Receptor in Mice Enhances Local Fatty Acid Trapping and Impairs Brown Adipose Tissue Thermogenesis

iScience, 2019
Summary: Growth hormone (GH) binds to its receptor (growth hormone receptor [GHR]) to exert its pleiotropic effects on growth and metabolism. Disrupted GH/GHR actions not only fail growth but also are involved in many metabolic disorders, as shown in ...
Liyuan Ran, Xiaoshuang Wang, Ai Mi, Yanshuang Liu, Jin Wu, Haoan Wang, Meihua Guo, Jie Sun, Bo Liu, Youwei Li, Dan Wang, Rujiao Jiang, Ning Wang, Wenting Gao, Li Zeng, Lin Huang, Xiaoli Chen, Derek LeRoith, Bin Liang, Xin Li, Yingjie Wu   +20 more
doaj   +1 more source

Growth hormone receptor promotes osteosarcoma cell growth and metastases

FEBS Open Bio, 2020
Osteosarcoma (OS) is the primary bone malignancy in children and adolescents, with a high incidence of lung metastasis and poor prognosis. Here, we report that growth hormone receptor (GHR) is overexpressed in OS samples compared with osteofibrous ...
Mo Cheng, Wending Huang, Weiluo Cai, Meng Fang, Yong Chen, Chunmeng Wang, Wangjun Yan   +6 more
doaj   +1 more source

Evaluation of the Sister Support Initiative

, 2023
GHR Foundation has a long history of partnering with Catholic sisters. We draw insight and inspiration from sisters, whose leadership, service, and spiritual witness have advanced the common good through a profound commitment to working on behalf of the ...

core   +2 more sources

Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons

Molecular Metabolism, 2017
Objective: The GH/IGF-1 axis has important roles in growth and metabolism. GH and GH receptor (GHR) are active in the central nervous system (CNS) and are crucial in regulating several aspects of metabolism. In the hypothalamus, there is a high abundance
Gillian Cady, Taylor Landeryou, Michael Garratt, John J. Kopchick, Nathan Qi, David Garcia-Galiano, Carol F. Elias, Martin G. Myers, Jr., Richard A. Miller, Darleen A. Sandoval, Marianna Sadagurski   +10 more
doaj   +1 more source

Relationship between of Exon 3 (+/-) Genotypes of Growth Hormone Receptor and Metabolic Risk Factors in Patients in Pre-diabetic State

مجله دانشکده پزشکی اصفهان, 2013
Background: Metabolic impacts of two important alleles of trh growth hormone receptors (GHR), one with retention of exon 3 [exon 3 (+) GHR] and the other with the deletion of it [exon 3 (-) GHR], on the metabolic risk factors of type 2 diabetes mellitus (
Gholam Basati, Zahra Valizadeh, Fatemeh Keshavarzi   +2 more
doaj  

The Associations of GH and GHR Genes with Carcass Components in Indonesian Kampung and Broiler Chicken Cross

Media Peternakan, 2017
The chicken growth hormone (GH) and its receptor (growth hormone receptor, GHR) play important roles in chicken performances due to their crucial functions in growth.
I. Khaerunnisa, Jakaria Jakaria, I. I. Arief, C. Budiman, C. Sumantri   +4 more
doaj   +1 more source