Results 71 to 80 of about 22,382 (200)
The Journal of biological chemistry, 2000 The growth hormone (GH) receptor (GHR) binds GH in its extracellular domain and transduces activating signals via its cytoplasmic domain. Both GH-induced GHR dimerization and JAK2 tyrosine kinase activation are critical in initiation of GH signaling. We previously described a rapid GH-induced disulfide linkage of GHRs in human IM-9 cells. In this study,
Y, Zhang +3 more
openaire +2 more sources
A Conformationally Sensitive GHR [Growth Hormone (GH) Receptor] Antibody: Impact on GH Signaling and GHR Proteolysis [PDF]
Molecular Endocrinology, 2004 The GH receptor (GHR) mediates metabolic and somatogenic actions of GH. Its extracellular domain (ECD; residues 1-246) has two subdomains, each with seven beta strands organized into two antiparallel beta sheets, connected by a short hinge region. Most of the ECD residues involved in GH binding reside in subdomain 1, whereas subdomain 2 harbors a ...
Jiang, J. +7 more
openaire +5 more sources
Expression analysis of ghr-miR482/miR482.2.
, 2013 A) Northern blot detection of ghr-miR482/482.2 in leaves collected from V. dahliae-infected and mock-treated cotton plants at one day-post-inoculation (1 dpi). Oligos antisense to ghr-miR482a and ghr-miR482e.2 were used together as probes.
Iain Wilson (430308) +5 more
core +1 more source
Polyphenism Through RNA Chemical Modifications
Molecular Ecology, Volume 35, Issue 19, October 2026.ABSTRACT Polyphenism, the capacity of a single genotype to produce discrete phenotypes in response to environmental cues, has long served as a model for understanding developmental plasticity. While classical studies have highlighted hormonal signalling and transcription‐factor‐driven gene regulatory networks that mediate these environmentally induced ...
Ralf Schneider, Ehsan Pashay Ahi
wiley +1 more source
, 2016 Nexus file containing phased alleles from GHR sequences of Sunda shelf Crocidura.
Handika, Heru +13 more
core +1 more source
Ghrelin and Ghrelin Receptor Modulation of Psychostimulant Action
Frontiers in Neuroscience, 2013 Ghrelin (GHR) is an orexigenic gut peptide that modulates multiple homeostatic functions including gastric emptying, anxiety, stress, memory, feeding and reinforcement.
Paul Jeff Wellman +2 more
doaj +1 more source
, 2013 Publication information, editorial details, copyright notice, and table of ...
Editor, GHR
core
Aromaticity in Octahedral Cyclopentadienylberyllium Transition Metal Clusters
European Journal of Inorganic Chemistry, Volume 29, Issue 26, 16 September 2026.Density functional theory studies on (CpBe)6M (M = Mn to Cu) complexes related to the experimentally known (CpBe)6Ni predict octahedral or distorted octahedral structures. The CpBe ligands are weak‐field ligands stabilizing high formal transition metal oxidation states by pπ → dπ forward electron donation to the central transition metal. (CpBe)6Ni is a
Huidong Li +7 more
wiley +1 more source
GH-induced and constitutive GHR endocytosis share the same characteristics.
, 2013 A. γ2A_GHR_Jak2 cells (left panel) and γ2A_GHR cells (right panel) were stimulated with 500 ng/ml GH for 90 min at 37°C as indicated. Total cell lysates (TCL) (lower panels) and GHR immunoprecipitates (upper panels) were analysed on western blot with the
Peter van Kerkhof (356257) +5 more
core +1 more source
ACR Open Rheumatology, Volume 8, Issue 9, September 2026.Objective Persistent pain affects around 20% of Australians after total knee replacement (TKR), yet no dedicated Australian model of care exists to address this unmet need. The Early Pain Intervention after Knee replacement (EPIK) model is being developed, informed by the effective and cost‐effective UK Support and Treatment After Replacement care ...
Navneet Chadha +45 more
wiley +1 more source