Results 61 to 70 of about 22,382 (200)
Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression
Annals of Neurology, Volume 100, Issue 4, Page 695-708, October 2026.Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low +11 more
wiley +1 more source
Direct actions of macronutrient components on goldfish hepatopancreas in vitro to modulate the expression of ghr-I, ghr-II, igf-I and igf-II mRNAs [PDF]
, 2017 In mammals and fish, somatic growth and metabolism are coordinated by the GH-IGF axis, composed of growth hormone (GH), growth hormone receptors I and II (GHR-I and GHR-II), and the insulin-like growth factors I and II (IGF-I and IGF-II).
Blanco, Ayelén Melisa +7 more
core +1 more source
Animals, 2020 The GH growth axis plays an important role in the growth and development of animals and runs through the whole life of animals. Many studies have shown that molecular mutations in key genes of the GH axis will affect the growth and development of animals.
Mingli Wu +6 more
doaj +1 more source
Distribution of Big Tau Isoforms in the Human Central and Peripheral Nervous System
Annals of Neurology, Volume 100, Issue 4, Page 709-736, October 2026.Objective Tau is widely studied in neurodegeneration, yet most work has focused on canonical brain tau isoforms. A longer isoform, “big tau,” produced by inclusion of exon 4a, is expressed in the peripheral nervous system (PNS) and central nervous system (CNS) regions.
Rama Krishna Koppisetti +17 more
wiley +1 more source
Evaluation of the GHR car following model for traffic safety studies [PDF]
, 2012 Traffic safety studies mandate more than what existing micro-simulation models can offer as they postulate that every driver exhibits a safe behaviour.
Miska, Marc +2 more
core
Frontiers in EndocrinologyBackgroundSkeletal fragility is characterized by increased frequency of vertebral fractures (VFs) in acromegaly. Several trials were conducted to identify modifiable risk factors and predictors of VFs, with limited data on the prognostic role of GH ...
Sabrina Chiloiro +24 more
doaj +1 more source
MicrobiologyOpen, Volume 15, Issue 5, October 2026.Green‐synthesized silver nanoparticles from Nepeta pogonosperma and Astrodaucus persicus significantly inhibit biofilm formation and downregulate bap gene expression in multidrug‐resistant clinical isolates of Acinetobacter baumannii. This eco‐friendly approach offers a promising strategy to combat antimicrobial resistance.
Maedeh Kakavan +6 more
wiley +1 more source
Deeper pipelines raise an FPGA soft core’s clock frequency, but they make every branch misprediction more costly. As depth grows, the global history register (GHR) of a correlation-based branch predictor takes longer to update. The register grows stale and inflates mispredictions, though the predictor hardware is unchanged.
Devansh Joshi, Shafin Ula
openaire +1 more source
GHR levels increase in the absence of SOCS2.
, 2013 (A) HEK293T cells were transfected with GHR and either SOCS2 or Control siRNA. Cells were starved for 4 hours and then treated with GH for the times indicated in the picture.
Michael Lund Nielsen (172389) +6 more
core +1 more source
四川大学学报. 自然科学版, 2015 本研究以猪作为研究模型,对GHR基因启动子区开展了克隆、转录因子结合位点分析和启动子活性鉴定.结果表明:家猪GHR基因或由两个启动子(GHR-P1和GHR-P2)控制.GHR-P1的部分核苷酸序列与牛、羊对应核苷酸序列具有较高的同源性,但功能分析显示其启动子活性较低.针对GHR-P2的实验结果表明其具有典型的GHR组成型启动子特征,荧光素酶报告实验表明其具有启动子活性,因此我们推测本次克隆获得的GHR-P2是猪GHR的组成型启动子.
徐敏 +4 more
doaj