Results 121 to 130 of about 38,958 (244)

Ghrelin Causes Hyperphagia and Obesity in Rats [PDF]

, 2001
Alison Wren, Caroline J. Small, Caroline R. Abbott, Waljit S. Dhillo, Leighton Seal, Mark A. Cohen, Rachel L. Batterham, Shahrad Taheri, Sarah A. Stanley, Mohammad A. Ghatei, Stephen R. Bloom   +10 more
openalex   +1 more source

Ghrelin transport across the blood–brain barrier can occur independently of the growth hormone secretagogue receptor

Molecular Metabolism, 2018
Objective: The blood–brain barrier (BBB) regulates the entry of substrates and peptides into the brain. Ghrelin is mainly produced in the stomach but exerts its actions in the central nervous system (CNS) by crossing the BBB.
Elizabeth M. Rhea, Therese S. Salameh, Sarah Gray, Jingjing Niu, William A. Banks, Jenny Tong   +5 more
doaj  

Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa [PDF]

, 2001
Bärbel Otto, Ulrich Cuntz, E Fruehauf, Rainer Wawarta, C Folwaczny, Riepl Rl, ML Heiman, P. Lehnert, Manfred M. Fichter, M. Tschöp   +9 more
openalex   +1 more source

The role of agomelatine in appetite regulation and body weight in rats

Experimental Physiology, EarlyView.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz, Yavuz Erden, Çiğdem Tekin, Suat Tekin   +3 more
wiley   +1 more source

Ghrelin, a Natural GH Secretagogue Produced by the Stomach, Induces Hyperglycemia and Reduces Insulin Secretion in Humans [PDF]

, 2001
Fabio Broglio, Emanuela Arvat, Andrea Benso, Cristina Gottero, Giampiero Muccioli, Mauro Papotti, Aart Jan van der Lely, Romano Deghenghi, Ezio Ghigo   +8 more
openalex   +1 more source

Incretin hormones and obesity

The Journal of Physiology, EarlyView.
Abstract figure legend The incretin system in obesity. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) (yellow) and glucagon‐like peptide‐1 (GLP‐1) (blue) are produced by the proximal and distal small intestinal epithelium, where they are released postprandially into the bloodstream to modulate a myriad of physiological and ...
Constanza Alcaino, Frank Reimann, Fiona M. Gribble   +2 more
wiley   +1 more source

Oxyntomodulin physiology and its therapeutic development in obesity and associated complications

The Journal of Physiology, EarlyView.
Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh, Ming Chuen Chong, Alexander D. Miras, Carel W. le Roux   +3 more
wiley   +1 more source

Ghrelin, A Novel Placental-Derived Hormone¹ [PDF]

, 2001
Oreste Gualillo, J. Eduardo Caminos, Montserrat Blanco, Tomás García‐Caballero, Masayasu Kojima, Kenji Kangawa, Carlos Diéguez, Felipe F. Casanueva   +7 more
openalex   +1 more source

Characterization of NTS‐to‐VTA projection neurons reveals higher‐order synaptic organization and distinct responsiveness to cholecystokinin

The Journal of Physiology, EarlyView.
Abstract figure legend Here we construct an anatomical map of brainstem projections to the ventral tegmental area (VTA) and investigate the neurochemical and neurophysiological nature of these VTA‐projecting nucleus of the solitary tract (NTS) neurons.
Caitlin R. Ritchey, David J. Rossi, James H. Peters   +2 more
wiley   +1 more source

The Novel Hypothalamic Peptide Ghrelin Stimulates Food Intake and Growth Hormone Secretion

, 2000
Alison Wren
openalex   +1 more source