Results 11 to 20 of about 38,787 (232)

Ghrelin: Ghrelin as a Regulatory Peptide in Growth Hormone Secretion [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Ghrelin is a type of growth hormone (GH) secretagogue that stimulates the release of GH. It is a first hormone linking gastrointestinal-pituitary axis.
Nazli Khatib, Shilpa Gaidhane, Abhay M Gaidhane, Mahanaaz Khatib, Padam Simkhada, Dilip Gode, Quazi Syed Zahiruddin   +6 more
doaj   +4 more sources

Ghrelin in the human myometrium [PDF]

Reproductive Biology and Endocrinology, 2010
Background Ghrelin is a 28-amino acid octanolyated peptide, synthesised primarily in the stomach. It stimulates growth hormone release, food intake and exhibits many other diverse effects. Our group have previously determined that ghrelin inhibited human
Morrison John J, Earley Padraig, O'Brien Margaret, Smith Terry J   +3 more
doaj   +4 more sources

GIST and Ghrelin: To Be or Not to Be? [PDF]

Diagnostics, 2021
Background: Ghrelin is the orexigenic hormone secreted mainly by the stomach. Its involvement in neoplastic development has been studied in gastrointestinal adenocarcinomas. Our paper aims to evaluate the influence of the ghrelin axis in gastrointestinal stromal tumors (GISTs). Materials and Methods: The study design included two groups of patients, 46
Irene Alexandra Spiridon, Delia Gabriela Apostol Ciobanu, Simona Eliza Giușcă, Dan Ferariu, Iulia Cătălina Pleşca, Irina Draga Căruntu   +5 more
openaire   +3 more sources

Ghrelin [PDF]

Molecular Metabolism, 2015
The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism.In this review, we discuss the diverse biological functions of ghrelin ...
Müller, T. D, Nogueiras, R., Andermann, M. L., Andrews, Z. B., Anker, S. D., Argente, J., Batterham, R. L., Benoit, S. C., Bowers, C. Y., BROGLIO, Fabio, Casanueva, F. F., D'Alessio, D., Depoortere, I., Geliebter, A., GHIGO, Ezio, Cole, P. A., Cowley, M., Cummings, D. E., Dagher, A., Diano, S., Dickson, S. L., Diéguez, C., GRANATA, Riccarda, Grill, H. J., Grove, K., Habegger, K. M., Heppner, K., Heiman, M. L., Holsen, L., Holst, B., Inui, A., Jansson, J. O., Kirchner, H., Korbonits, M., Laferrère, B., Leroux, C. W., Lopez, M., Morin, S., Nakazato, M., Nass, R., Perez Tilve, D., Pfluger, P. T., Schwartz, T. W., Seeley, R. J., Sleeman, M., Sun, Y., Sussel, L., Tong, J., Thorner, M. O., van der Lely, A. J., van der Ploeg, L. H. T., Zigman, J. M., Kojima, M., Kangawa, K., Smith, R. G., Horvath, T., Tschöp, M. H.   +56 more
openaire   +7 more sources

Update on Ghrelin [PDF]

International Journal of Peptides, 2010
Few peptide hormones have attracted as much attention of the scientific community as ghrelin, the natural secretagogue for growth hormone (GH) identified by M. Kojima et al. in 1999 [1], resulting in more than 4000 PubMed citations over the last ten years. The initial interest can be attributed to the ability of ghrelin to stimulate feeding in mammals,
S. O. FETISSOV, LAVIANO, Alessandro, S. KALRA, A. INUI   +3 more
openaire   +3 more sources

Starving for Ghrelin [PDF]

Cell Metabolism, 2014
The initial discovery of ghrelin as a potent orexigenic hormone raised excitement about a new direction for possibly treating eating disorders. McFarlane et al. (2014) show that with deletion of ghrelin-producing cells from an adult animal, there is little effect on appetitive behaviors but significant implications for glucose homeostasis.
David Spanswick, Mark W. Sleeman
openaire   +3 more sources

The Role of Ghrelin and Ghrelin Signaling in Aging [PDF]

International Journal of Molecular Sciences, 2017
With our aging society, more people hope for a long and healthy life. In recent years, researchers have focused on healthy longevity factors. In particular, calorie restriction delays aging, reduces mortality, and extends life. Ghrelin, which is secreted during fasting, is well known as an orexigenic peptide.
Marie Amitani, Haruka Amitani, Kai-Chun Cheng, Timothy Sean Kairupan, Nanami Sameshima, Ippei Shimoshikiryo, Kimiko Mizuma, Natasya Trivena Rokot, Yasuhito Nerome, Tetsuhiro Owaki, Akihiro Asakawa, Akio Inui   +11 more
openaire   +2 more sources

Ghrelin for cachexia [PDF]

Journal of Cachexia, Sarcopenia and Muscle, 2010
Ghrelin, a natural ligand for the growth hormone (GH)‐secretagogue receptor, is primarily produced in the stomach. Administration of ghrelin stimulates food intake and GH secretion in both animals and humans. Ghrelin is the only circulating hormone known to stimulate appetite in humans.
Takashi Akamizu, Kenji Kangawa
openaire   +3 more sources

Altered lipid and salt taste responsivity in ghrelin and GOAT null mice. [PDF]

PLoS ONE, 2013
Taste perception plays an important role in regulating food preference, eating behavior and energy homeostasis. Taste perception is modulated by a variety of factors, including gastric hormones such as ghrelin. Ghrelin can regulate growth hormone release,
Huan Cai, Wei-Na Cong, Caitlin M Daimon, Rui Wang, Matthias H Tschöp, Jean Sévigny, Bronwen Martin, Stuart Maudsley   +7 more
doaj   +1 more source

Insights from engraftable immunodeficient mouse models of hyperinsulinaemia

Scientific Reports, 2017
Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1 −/−) suitable for ...
Michelle L. Maugham, Patrick B. Thomas, Gabrielle J. Crisp, Lisa K. Philp, Esha T. Shah, Adrian C. Herington, Chen Chen, Laura S. Gregory, Colleen C. Nelson, Inge Seim, Penny L. Jeffery, Lisa K. Chopin   +11 more
doaj   +1 more source