Ghrelin is Impacted by the Endogenous Circadian System and by Circadian Misalignment in Humans
The human circadian system regulates hunger independently of behavioral factors, resulting in a trough in the biological morning and a peak in the biological evening.
J. Qian+4 more
semanticscholar +1 more source
Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]
Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
core
Weight gain and metabolic disruptions are common in children and adolescents treated with antipsychotics, but the underlying mechanisms are unclear, complicating prevention and treatment. This study examines the impact of risperidone on appetite‐regulating hormones (insulin, leptin and bioleptin) and their relationship to body weight changes over time.
Jiayi Liang+10 more
wiley +1 more source
Ghrelin and reproductive disorders [PDF]
Ghrelin is an important factor involved in most of the metabolic and hormonal signals which adapt the reproductive functions in conditions of altered energy balance. Moreover, the coordinated role of leptin and ghrelin appears in fact to have a specific role in the regulation of puberty.
REPACI, ANDREA+3 more
openaire +6 more sources
How Do Individually Ventilated Cages Affect the Welfare of Male BALB/c Mice? Comprehensive Assessment of Behavior, Metabolism, and Responses to Acute Painful Stimuli [PDF]
IVC housing conditions cause significant changes in behavioral patterns, metabolism, and nociceptive responses in mice. ABSTRACT Introduction Housing conditions, which have a major impact on the welfare of laboratory animals, are an important issue in experimental research.
Çelik A+7 more
europepmc +2 more sources
Attribution of ghrelin to cancer; Attempts to unravel an apparent controversy [PDF]
Ghrelin is an endogenous peptide hormone mainly produced in the stomach. It has been known to regulate energy homeostasis, stimulate secretion of growth hormone, and mediate many other physiologic effects. Various effects attributed to ghrelin contribute
Khani, Leila+5 more
core +1 more source
Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study. [PDF]
As perspectives on cannabis continue to shift, understanding the physiological and behavioral effects of cannabis use is of paramount importance. Previous data suggest that cannabis use influences food intake, appetite, and metabolism, yet human research
Abulseoud, Osama A+6 more
core +1 more source
Cancer anorexia: hypothalamic activity and its association with inflammation and appetite-regulating peptides in lung cancer [PDF]
Background Energy homeostasis is mediated by the hypothalamus, whose inflammation-induced functional derangements contribute to the onset of anorexia in cancer.
Arezzo di Trifiletti+39 more
core +1 more source
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis+2 more
wiley +1 more source
MOLECULAR EVOLUTION OF GPCRS: Ghrelin/ghrelin receptors [PDF]
After the discovery in 1996 of the GH secretagogue-receptor type-1a (GHS-R1a) as an orphan G-protein coupled receptor, many research groups attempted to identify the endogenous ligand. Finally, Kojima and colleagues successfully isolated the peptide ligand from rat stomach extracts, determined its structure, and named it ghrelin.
Kenji Kangawa+2 more
openaire +3 more sources