Results 31 to 40 of about 20,015 (204)
Ghrelin accelerates growth of olfactory ensheathing cells through ERK pathway
Indian Journal of Animal Sciences, 2016 Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), stimulates growth hormone (GH) secretion and has both orexigenic and adipogenic effects.
PEI ZHANG +6 more
doaj +1 more source
GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus [PDF]
Advanced Pharmaceutical Bulletin, 2013 Purpose: Ghrelin has been shown to have antiepileptic function. However, the underlying mechanisms by which, ghrelin exerts its antiepileptic effects are still unclear.
Zohreh Ataie +5 more
doaj +1 more source
The effects of diet and chronic exercise on skeletal muscle ghrelin response
Metabolism Open, 2022 Background: Recent findings indicate that ghrelin, particularly the unacylated form (UnAG), acutely stimulates skeletal muscle fatty acid oxidation (FAO) and can preserve insulin signaling and insulin-stimulated glucose uptake in the presence of high ...
Andrew J. Lovell +4 more
doaj +1 more source
Function of ghrelin and ghrelin receptors in the network regulation of gastric motility
Molecular Medicine Reports, 2014 Numerous previous studies have demonstrated that ghrelin promotes gastric motility when administered peripherally. This effect appears to be regulatory but not directly stimulatory, and therefore may involve a number of complex mechanisms. In the periphery, ghrelin may affect gastric motility through intercellular networks among interstitial cells of ...
Cheng-Guang, Yang +4 more
openaire +3 more sources
The Complex Signaling Pathways of the Ghrelin Receptor
Endocrinology, 2020 AbstractThe ghrelin receptor (GhrR) is known for its strong orexigenic effects in pharmacological doses and has long been considered as a promising target for the treatment of obesity. Several antagonists have been developed to decrease the orexigenic signaling, but none of these have been approved for the treatment of obesity because of adverse ...
Morten Adler Hedegaard, Birgitte Holst
openaire +4 more sources
Novel and Conventional Receptors for Ghrelin, Desacyl-Ghrelin, and Pharmacologically Related Compounds [PDF]
Pharmacological Reviews, 2014 The only molecularly identified ghrelin receptor is the growth hormone secretagogue receptor GHSR1a. Its natural ligand, ghrelin, is an acylated peptide whose unacylated counterpart (UAG) is almost inactive at GHSR1a. A truncated, nonfunctional receptor, GHSR1b, derives from the same gene.
Callaghan, B, Furness, JB
openaire +3 more sources
Multiple roles of ghrelin in breast cancer
The International Journal of Biological Markers, 2022 Breast cancer is one of the most threatening malignant tumors in women worldwide; hence, investigators are continually performing novel research in this field. However, an accurate prediction of its prognosis and postoperative recovery remains difficult.
Yiding Chen +6 more
doaj +1 more source
Neuromorphic Devices and Computing for Sensing, Memory, and Control
Advanced Science, EarlyView.This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages. [PDF]
PLoS ONE, 2009 The peroxisome proliferator-activator receptor PPARgamma plays an essential role in vascular biology, modulating macrophage function and atherosclerosis progression.
Annie Demers +5 more
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source