Studies on the antidepressant-like effect and prokinetic-like effects and the underlying mechanisms of Fructus aurantii and meranzin hydrate [PDF]
目的:测定代表中药枳壳汤剂抗抑郁促动力(A&P)的吸收成分,初步阐明其A&P特别是抗抑郁的作用机理。 方法:1.含量测定。运用HPLC/MS/MS测定枳壳汤剂在空肠,海马和前额叶皮层吸收成分;2.急性抗抑郁疗效测试。该实验包括枳壳汤剂及其吸收成分水合橙皮内酯的急性抗抑郁疗效测试。该测试包括强迫游泳实验、旷场实验、习得性无助实验和新奇抑制实验;3.水合橙皮内酯的慢性抗抑郁疗效测试。包括强迫游泳实验和旷场实验;4.离体和在体胃肠动力实验;5.抗抑郁机制研究和抗抑郁促动力的共性机制研究 ...
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Expression patterns of GHRL, GHSR, LEP, LEPR, SST and CCK genes in the gastrointestinal tissues of Tibetan and Yorkshire pigs [PDF]
Wenkui Sun +9 more
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A large and unusual lung abscess with positive culture to Slackia exigua
C. Roingeard +2 more
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Pesquisa de mutações no gene do receptor do secretagogo de hormônio de crescimento (GHSR) em crianças com baixa estatura idiopática e deficiência isolada de hormônio de crescimento [PDF]
Patrícia Nascimbem Pugliese Pires
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Pharmacological GHSR (ghrelin receptor) blockade reduces alcohol binge-like drinking in male and female mice [PDF]
Rani S. Richardson +8 more
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9293 Do Obesity-Associated MRAP2 Variants Modulate MC4R and GHSR Signaling?
Abstract Disclosure: A.V. Rodriguez Rondon: None. F. Volker: None. M.S. Welling: None. C. de Groot: None. M.M. van Haelst: None. E.L. van den Akker: None. E.F. van Rossum: None. P.J. Delhanty: None. J.A. Visser: None. Melanocortin 2 receptor accessory protein 2 (MRAP2) is a membrane-bound protein expressed on hypothalamic ...
Rondon, Alejandra Virginia Rodriguez +8 more
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The Ghsr Q343X allele favors the storage of fat by acting on nutrient partitioning [PDF]
Candice Marion +8 more
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GHSR suppression in neurons protects against aging-associated metabolic and cognitive impairments
Abstract Aging is accompanied by progressive declines in metabolic and cognitive functions. Growth hormone secretagogue receptor (GHSR), a receptor for the gut hormone ghrelin, is highly expressed in neurons and plays a crucial role in metabolic regulation.
Hongying Wang +10 more
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