Escalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling [PDF]
, 2015 Binge eating is a behavior observed in a variety of human eating disorders. Ad libitum fed rodents daily and time-limited exposed to a high-fat diet (HFD) display robust binge eating events that gradually escalate over the initial accesses.
Cornejo, María P. +4 more
core +2 more sources
Smartphone based music intervention in the treatment of episodic migraine headaches – A pilot trial
Complementary Therapies in Medicine, 2021 Objectives: Migraine headaches are a prevalent and burdening disorder for the public worldwide. Both traditional preventive drugs and behavioral-based interventions have been used as treatment in the prevention of migraine attacks.
Guilhem Parlongue +3 more
doaj +1 more source
Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease [PDF]
, 2016 Jacqeline Bayliss, Romana Stark, Moyra Lemus, Vanessa Santos, Aiysha Thompson, Daniel Rees, Sandra Galic, John Elsworth, Bruce Kemp, Jeffrey Davies, and Zane ...
Andrews, Zane B. +10 more
core +1 more source
The Pathologic Roles and Therapeutic Implications of Ghrelin/GHSR System in Mental Disorders
Depression and AnxietyGhrelin is a hormone consisting of 28 amino acids. Growth hormone secretagogue receptor (GHSR) is a receptor for ghrelin, which is expressed in the brain, pituitary gland, and adrenal glands, especially in the hypothalamus. The binding of ghrelin to the receptor 1a subtype mediates most of the biological effects of ghrelin.
Qiao Mao +5 more
openalex +3 more sources
Proposal for the nomination of Lower Globigerina Limestone of the Maltese Islands as a "Global Heritage Stone Resource" [PDF]
, 2017 The Lower Globigerina Limestone of the Maltese Islands is here being proposed for nomination as a “Global Heritage Stone Resource”. This stone, continuously used for building and sculpture for 6000 years, is well suited to fit this global designation as ...
Cassar, JoAnn +3 more
core +1 more source
Attribution of ghrelin to cancer; Attempts to unravel an apparent controversy [PDF]
, 2019 Ghrelin is an endogenous peptide hormone mainly produced in the stomach. It has been known to regulate energy homeostasis, stimulate secretion of growth hormone, and mediate many other physiologic effects. Various effects attributed to ghrelin contribute
Khani, Leila +5 more
core +1 more source
Pharmacogenomic and structural analysis of constitutive G-protein coupled receptor activity [PDF]
, 2007 Premi a l'excel·lència investigadora. Àmbit de les Ciències de la Salut. 2008G-protein coupled receptors (GPCRs) respond to a chemically diverse plethora of signal transduction molecules.
Aldo Jongejan +29 more
core +3 more sources
Animals, 2022 Ghrelin O-acyltransferase (GOAT), ghrelin, and GHSR have been reported to play important roles that influence feed intake in mammals. LEAP2, an endogenous antagonist of GHSR, plays an important role in the regulation of feed intake.
Xiaotong Zheng +6 more
doaj +1 more source
Ghrelin accelerates synapse formation and activity development in cultured cortical networks [PDF]
, 2014 Background: While ghrelin was initially related to appetite stimulation and growth hormone secretion, it also has a neuroprotective effect in neurodegenerative diseases and regulates cognitive function. The cellular basis of those processes is related to
Feber, J. le, Stoyanova, I.I.
core +2 more sources
Ghrelin Receptor Is Required for the Effect of Nesfatin-1 on Glucose Metabolism
Frontiers in Endocrinology, 2018 Studies of nesfatin-1 in glucose metabolism have become a topic of interest recently, however, the specific receptor for nesfatin-1 has not yet been identified.
Xin-Tong Fan +11 more
doaj +1 more source