Attribution of ghrelin to cancer; Attempts to unravel an apparent controversy [PDF]
Ghrelin is an endogenous peptide hormone mainly produced in the stomach. It has been known to regulate energy homeostasis, stimulate secretion of growth hormone, and mediate many other physiologic effects. Various effects attributed to ghrelin contribute
Khani, Leila +5 more
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Ghrelin accelerates synapse formation and activity development in cultured cortical networks [PDF]
Background: While ghrelin was initially related to appetite stimulation and growth hormone secretion, it also has a neuroprotective effect in neurodegenerative diseases and regulates cognitive function. The cellular basis of those processes is related to
Feber, J. le, Stoyanova, I.I.
core +2 more sources
Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study [PDF]
Background: Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor (GHSR), has two major functions: the stimulation of the growth hormone production and the stimulation of food intake.
Campa, Daniele +23 more
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Smartphone based music intervention in the treatment of episodic migraine headaches – A pilot trial
Objectives: Migraine headaches are a prevalent and burdening disorder for the public worldwide. Both traditional preventive drugs and behavioral-based interventions have been used as treatment in the prevention of migraine attacks.
Guilhem Parlongue +3 more
doaj +1 more source
Proposal for the nomination of Lower Globigerina Limestone of the Maltese Islands as a "Global Heritage Stone Resource" [PDF]
The Lower Globigerina Limestone of the Maltese Islands is here being proposed for nomination as a “Global Heritage Stone Resource”. This stone, continuously used for building and sculpture for 6000 years, is well suited to fit this global designation as ...
Cassar, JoAnn +3 more
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Ghrelin Receptor Is Required for the Effect of Nesfatin-1 on Glucose Metabolism
Studies of nesfatin-1 in glucose metabolism have become a topic of interest recently, however, the specific receptor for nesfatin-1 has not yet been identified.
Xin-Tong Fan +11 more
doaj +1 more source
Ghrelin O-acyltransferase (GOAT), ghrelin, and GHSR have been reported to play important roles that influence feed intake in mammals. LEAP2, an endogenous antagonist of GHSR, plays an important role in the regulation of feed intake.
Xiaotong Zheng +6 more
doaj +1 more source
The Ghrelin Receptor Ghsr Has Two Efficient Agonists in an Ancient Fish Species
AbstractThe gastric peptide ghrelin and its receptor GHSR have important functions in energy metabolism. Recently, liver-expressed antimicrobial peptide 2 (LEAP2) was identified as an endogenous antagonist for GHSR. Ghrelin, LEAP2, and GHSR are ubiquitously present from fishes to mammals and are highly conserved in evolution.
Hao‐Zheng Li +5 more
openalex +2 more sources
Pharmacogenomic and structural analysis of constitutive G-protein coupled receptor activity [PDF]
Premi a l'excel·lència investigadora. Àmbit de les Ciències de la Salut. 2008G-protein coupled receptors (GPCRs) respond to a chemically diverse plethora of signal transduction molecules.
Aldo Jongejan +29 more
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Catestatin and GABAAR related feeding habits rely on dopamine, ghrelin plus leptin neuroreceptor expression variations [PDF]
Catestatin (CST), an endogenously small sympathoinhibitory peptide is capable of interfering with the major cerebral neuroreceptor-blocking site, i.e. γ-aminobutyric acidA receptor (GABAAR) system especially in limbic brain areas that are involved with ...
Alò, Raffaella +7 more
core +1 more source

