Results 41 to 50 of about 6,435 (196)

Ghrelin/GHSR Axis Induced M2 Macrophage and Alleviated Intestinal Barrier Dysfunction in a Sepsis Rat Model by Inactivating E2F1/NF-κB Signaling

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2023
Sepsis is an inflammatory reaction disorder state that is induced by infection. The activation and regulation of the immune system play an essential role in the development of sepsis.
Lei Zhu   +7 more
doaj   +1 more source

Familial partial lipodystrophy type 2 and obesity, two adipose tissue pathologies with different inflammatory profiles

open access: yesDiabetology & Metabolic Syndrome, 2023
Introduction The transition to metabolically unhealthy obesity (MUO) is driven by the limited expandability of adipose tissue (AT). Familial Partial Lipodystrophy type 2 (FPLD2) is an alternative model for AT dysfunction that is suitable for comparison ...
Guillaume Treiber   +7 more
doaj   +1 more source

The ghrelinergic system in zebrafish gonads is suppressed during food unavailability

open access: yesAquaculture and Fisheries, 2022
Ghrelin is an appetite stimulatory peptide that regulates reproduction in vertebrates. The acylation of ghrelin by ghrelin-O-acyltransferase (Goat) is essential for most of its functions. The ghrelinergic system (ghrelin, ghrelin receptor [Ghsr] and Goat)
Azadeh Hatef   +2 more
doaj   +1 more source

Genetic determination of the cellular basis of the ghrelin-dependent bone remodeling

open access: yesMolecular Metabolism, 2015
Objective: Bone mass is maintained through a balance of bone formation and resorption. This homeostatic balance is regulated by various systems involving humoral and local factors.
Chengshan Ma   +7 more
doaj   +1 more source

Association Analysis of the Leptin and Ghrelin Receptor Gene Polymorphism in the Human with BMI

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The aim of this work was identification of Leptin and Ghrelin receptor gene polymorphism in the population. Leptin is a product of obese (ob) gene expression that plays a role in energy metabolism and body weight.
Zuzana Lieskovská   +4 more
doaj  

Variations in the ghrelin receptor gene associate with obesity and glucose metabolism in individuals with impaired glucose tolerance. [PDF]

open access: yesPLoS ONE, 2008
Ghrelin may influence the development of obesity through its role in the control of energy balance, food intake, and regulation of body weight. The effects of ghrelin are mediated via the growth hormone secretagogue receptor (GHSR).We genotyped 7 single ...
Ursula Mager   +10 more
doaj   +1 more source

Sodium is a negative allosteric regulator of the ghrelin receptor

open access: yesCell Reports, 2023
Summary: The functional properties of G protein-coupled receptors (GPCRs) are intimately associated with the different components in their cellular environment.
Guillaume Ferré   +8 more
doaj   +1 more source

GHSR mRNA expression is restored selectively in the hindbrain in GHSR-null/Phox2b mice.

open access: yes, 2013
Coronal sections of a representative wild-type mouse brain demonstrating expression in the nucleus of the solitary tract, area postrema and vagus motor nerve (A, NTS, AP, DMV), nucleus ambiguus (B, Amb), 7th nerve (C, nVII) and the arcuate nucleus of the
Jen-Chieh Chuang (309076)   +8 more
core   +1 more source

Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity. [PDF]

open access: yesPLoS ONE, 2010
The growth hormone secretagogue receptor (GHSR) is mediating hunger sensation when stimulated by its natural ligand ghrelin. In the present study, we tested the hypothesis that common and rare variation in the GHSR locus are related to increased ...
Anette P Gjesing   +20 more
doaj   +1 more source

Large Datasets for the Euro Area and Its Member Countries and the Dynamic Effects of the Common Monetary Policy

open access: yesJournal of Applied Econometrics, EarlyView.
ABSTRACT We introduce EA‐MD‐QD, a new publicly available dataset comprising 1136 macroeconomic time series for the euro area (EA) and its ten largest member countries observed at monthly or quarterly frequency. Since January 2024, EA‐MD‐QD has been updated monthly and continuously revised, providing a valuable resource for policy analysis in the EA ...
Matteo Barigozzi   +2 more
wiley   +1 more source

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