Results 61 to 70 of about 5,420 (161)
Ghrelin mediates exercise endurance and the feeding response post-exercise
Molecular Metabolism, 2018 Objective: Exercise training has several well-established health benefits, including many related to body weight, appetite control, and blood glucose homeostasis. However, the molecular mechanisms and, in particular, the hormonal systems that mediate and
Bharath K. Mani +6 more
doaj +1 more source
JCI Insight, 2023 Previous studies have implicated the orexigenic hormone ghrelin as a mediator of exercise endurance and the feeding response postexercise. Specifically, plasma ghrelin levels nearly double in mice when they are subjected to an hour-long bout of high ...
Omprakash Singh +11 more
doaj +1 more source
Allosteric modulation of ghrelin receptor signaling by lipids
Nature Communications, 2021 The membrane is an integral component of the G protein-coupled receptor signaling machinery. Here authors demonstrate that lipids regulate the signaling efficacy and selectivity of the ghrelin receptor GHSR through specific interactions and bulk effects ...
Marjorie Damian +11 more
doaj +1 more source
Ghrelin enhances tubular magnesium absorption in the kidney
Frontiers in PhysiologyOsteoporosis after bariatric surgery is an increasing health concern as the rate of bariatric surgery has risen. In animal studies mimicking bariatric procedures, bone disease, together with decreased serum levels of Ca2+, Mg2+ and the gastric hormone ...
Mingzhu Nie +11 more
doaj +1 more source
Chloride Balance in Preterm Infants during the First Week of Life
International Journal of Pediatrics, 2012 Objective. To describe the chloride balance in infants born 25–32-week gestation, analyze the association of chloride changes with hydroelectrolytic status and their relationship with perinatal conditions, morbidities, and neurological outcome.
Silvia Iacobelli +4 more
doaj +1 more source
A Sleep‐Specific Midbrain Target for Sevoflurane Anesthesia
Advanced Science, 2023 Sevoflurane has been the most widely used inhaled anesthetics with a favorable recovery profile; however, the precise mechanisms underlying its anesthetic action are still not completely understood.
Tingting Yi +21 more
doaj +1 more source
Advanced Science, Volume 13, Issue 8, 9 February 2026.This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen +31 more
wiley +1 more source
Mutations in the ghrelin receptor gene GHSR in congenital hypopituitarism
Problems of Endocrinology, 2017 The results of molecular genetic studies indicate the potential involvement of ghrelin in the pathogenesis of some dwarfism forms. However, in the case of isolated somatotropin insufficiency, mutations in the ghrelin receptor gene are a rare cause of the disease.
Elena B. Bashnina +6 more
openaire +2 more sources
Myeloid GHSR Deficiency Protects Against Endotoxemia via Macrophage Mitochondrial Reprogramming
BiomedicinesBackground: Endotoxemia is a severe inflammatory condition that is characterized by acute immune responses and oxidative stress; endotoxemia can further develop into a cytokine storm and sepsis leading to severe organ damage.
Da Mi Kim +10 more
doaj +1 more source
Folia Histochemica et Cytobiologica, 2010 The results of presented study demonstrate expression of ghrelin, its functional receptor GHSR-1a and their genes in spermatogenic cells of rat testis suggesting their functioning within seminiferous epithelium.
Marcin Ruciński +7 more
doaj +1 more source