Results 61 to 70 of about 6,435 (196)

Ghrelin receptor expression and colocalization with anterior pituitary hormones using a GHSR-GFP mouse line

, 2012
Ghrelin is the endogenous ligand for the GH secretagogue receptor (GHSR) and robustly stimulates GH release from the anterior pituitary gland. Ghrelin also regulates the secretion of anterior pituitary hormones including TSH, LH, prolactin (PRL), and ...
Reichenbach, Alex, Sleeman, Mark W., Steyn, Frederick J., Andrews, Zane B.   +3 more
core   +1 more source

Milk and infant plasma hormone concentrations predict sweet and fat taste acceptance and later food intake

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Early‐life exposure to metabolic hormones may influence the development of taste acceptance and subsequent intake of hyperpalatable foods (HPF) in infants, but evidence integrating hormonal, behavioral, and dietary data in humans is limited.
Ana Luz Kruger, Agustina Malpeli, Marisa Sala, Carla Casado, Ignacio Mendez, Lucrecia Fotia, Mercedes López, María Silvina Faquini, Daniel Castrogiovanni, Helgi Schioth, Sophie Nicklaus, Mario Perello, María F. Andreoli   +12 more
wiley   +1 more source

Chicken LEAP2 Level Substantially Changes with Feed Intake and May Be Regulated by CDX4 in Small Intestine

Animals, 2022
Ghrelin O-acyltransferase (GOAT), ghrelin, and GHSR have been reported to play important roles that influence feed intake in mammals. LEAP2, an endogenous antagonist of GHSR, plays an important role in the regulation of feed intake.
Xiaotong Zheng, Ziwei Chen, Wuchao Zhuang, Jilong Zhang, Jiaheng He, Yinku Xie, Jianfei Chen   +6 more
doaj   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, Volume 58, Issue 5, Page 1413-1444, September 2026.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Ghrelin Modulates Physiologic and Pathologic Retinal Angiogenesis through GHSR-1a

, 2017
PURPOSE: Vascular degeneration and the ensuing abnormal vascular proliferation are central to proliferative retinopathies. Given the metabolic discordance associated with these diseases, the authors explored the role of ghrelin and its growth hormone ...
Stahl, Andreas, Lachapelle, Pierre, Zaniolo, Karine, Zhu, Tang, Hardy, Pierre, Picard, Emilie, Smith, Lois, Blais, Martine, Madaan, Ankush, Mancini, Joseph, Ong, Huy, Chemtob, Sylvain, Sapieha, Przemyslaw, Shao, Zhuo, Tremblay, Sophie   +14 more
core   +1 more source

Synthetic Food Colorants and Gut Microbiota: A Systematic Review of Preclinical Studies

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT Growing evidence suggests that industrial food processing, including the excess consumption of food additives, might have a negative impact on human health. Despite regulatory safety evaluations, their impact on gut microbiota remains poorly characterized.
Sebastiano Alfio Torrisi, Federica Martina Di Domenico, Gian Marco Leggio, Giuseppe Caruso, Evelyn Frias‐Toral, Nohora Milena Martínez López, Agnieszka Micek, Marialaura Bonaccio, Justyna Godos, Giuseppe Grosso   +9 more
wiley   +1 more source

Molecular cloning and expression characteristics of ghrl and ghsr genes in bighead carp (Hypophthalmichthys nobilis)

Aquaculture and Fisheries
Ghrelin (ghrl) and its receptor gene ghsr (growth hormone secretagogue receptor) regulate numerous physiological functions, including growth hormone secretion and food intake.
Pan Wang, Jianjun Fu, Mingkun Luo, Xiulan Shi, Wenbin Zhu, Lanmei Wang, Shichang Shu, Zaijie Dong   +7 more
doaj   +1 more source

Alcohol Exposure Alters the Ghrelin System: In Vitro Mechanistic Insights Into Impaired Glucose Sensing and Enhanced Ghrelin Secretion

Alcohol, Clinical and Experimental Research, Volume 50, Issue 8, August 2026.
Chronic ethanol exposure increases ghrelin production by impairing glucose sensing in ghrelin‐secreting cells. Ethanol elevates ghrelin and ghrelin O‐acyltransferase expression, blunts glucose‐mediated suppression, and synergizes with fatty acids to enhance secretion.
Sundararajan Mahalingam, Ramesh Bellamkonda, Kusum K. Kharbanda, Ojeshvi Ethiraj, Carol A. Casey, Karuna Rasineni   +5 more
wiley   +1 more source

Enhanced responsiveness of Ghsr Q343X rats to ghrelin results in enhanced adiposity without increased appetite

, 2016
International audienceThe ability of the gut hormone ghrelin to promote positive energy balance is mediated by the growth hormone secretagogue receptor (GHSR).
Geny, David, Chebani, Yacine, Epelbaum, Jacques, Zizzari, Philippe, Tolle, Virginie, Marion, Candice, Korostelev, Marie, Pantel, Jacques, Pastor, Marie, Morisset-Lopez, Séverine, Chettab, Khadidja   +10 more
core   +1 more source

Novel Long‐Acting Ghrelin Analogue PEP‐064 Restores Energy Balance in C26 and Lewis Lung Carcinoma–Induced cachexia in Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia is a debilitating syndrome marked by involuntary weight loss resulting from reduced food intake and intricate metabolic reprogramming. Despite its high prevalence, cancer cachexia remains undertreated, with a lack of effective and approved pharmacotherapies.
J. E. Hunt, C. Lund, B. Chen, A. R. Diaz, O. Dmytriyeva, J. Marcotorchino, K. Löbner, K. Mörl, N. R. Andersen, Z. K. J. Ogueboule, E. Frank, J. Stöhr, D. Meseguer, V. Panajotova, J. Roux, C. Clemmensen, L. Sylow, M. Schneeberger, A. G. Beck‐Sickinger, S. L. Pedersen, K. Fosgerau   +20 more
wiley   +1 more source