Results 71 to 80 of about 6,435 (196)
Molecular MetabolismObjective: Obesity-associated chronic inflammation, aka meta-inflammation, is a key pathogenic driver for obesity-associated comorbidity. Growth hormone secretagogue receptor (GHSR) is known to mediate the effects of nutrient-sensing hormone ghrelin in ...
Da Mi Kim +13 more
doaj +1 more source
Allosteric modulation of ghrelin receptor signaling by lipids
Nature Communications, 2021 The membrane is an integral component of the G protein-coupled receptor signaling machinery. Here authors demonstrate that lipids regulate the signaling efficacy and selectivity of the ghrelin receptor GHSR through specific interactions and bulk effects ...
Marjorie Damian +11 more
doaj +1 more source
Altered responses to ghrelin and food cues in AgRP neurons during pregnancy and lactation
Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.Abstract Pregnancy and lactation trigger many metabolic adaptations, including increased food intake to support the energy demands of the growing foetus and then to provide nutrition through milk production after birth. Ghrelin, an orexigenic hormone, activates agouti related peptide (AgRP) neurons in the arcuate nucleus to promote food intake.
C. L. Murrell +4 more
wiley +1 more source
JCI Insight, 2023 Previous studies have implicated the orexigenic hormone ghrelin as a mediator of exercise endurance and the feeding response postexercise. Specifically, plasma ghrelin levels nearly double in mice when they are subjected to an hour-long bout of high ...
Omprakash Singh +11 more
doaj +1 more source
Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.Abstract Roux‐en‐Y gastric bypass (RYGB) is an effective surgical intervention for severe obesity, but the role of gastrointestinal hormones in its benefits remains unclear. We examined longitudinal pre‐to‐post‐meal gastrointestinal hormone changes and their relationships with glucose homeostasis and feeding‐related cognitive responses in women ...
María F. Andreoli +8 more
wiley +1 more source
Chloride Balance in Preterm Infants during the First Week of Life
International Journal of Pediatrics, 2012 Objective. To describe the chloride balance in infants born 25–32-week gestation, analyze the association of chloride changes with hydroelectrolytic status and their relationship with perinatal conditions, morbidities, and neurological outcome.
Silvia Iacobelli +4 more
doaj +1 more source
Ghrelin mediates exercise endurance and the feeding response post-exercise
Molecular Metabolism, 2018 Objective: Exercise training has several well-established health benefits, including many related to body weight, appetite control, and blood glucose homeostasis. However, the molecular mechanisms and, in particular, the hormonal systems that mediate and
Bharath K. Mani +6 more
doaj +1 more source
A Sleep‐Specific Midbrain Target for Sevoflurane Anesthesia
Advanced Science, 2023 Sevoflurane has been the most widely used inhaled anesthetics with a favorable recovery profile; however, the precise mechanisms underlying its anesthetic action are still not completely understood.
Tingting Yi +21 more
doaj +1 more source
Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases
Prenatal Diagnosis, Volume 46, Issue 5-6, Page 849-861, May 2026.ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei +9 more
wiley +1 more source
CRF-IR neurons of the PVN do not express GHSR.
, 2013 Upper panels show representative ISHH photomicrographs of thionin counterstained coronal sections of brain mouse. Panels A and B show photomicrographs of the ARC and PVN, respectively.
Olga Suescun (332164) +3 more
core +1 more source