Ghrelin O-acyltransferase (GOAT), ghrelin, and GHSR have been reported to play important roles that influence feed intake in mammals. LEAP2, an endogenous antagonist of GHSR, plays an important role in the regulation of feed intake.
Xiaotong Zheng +6 more
doaj +1 more source
Obesity-Induced PVAT Dysfunction and Atherosclerosis Development: The Role of GHSR-1a in Increased Macrophage Infiltration and Adipocytokine Secretion. [PDF]
In obesity, recent research revealed that increased expression of the growth hormone secretagogue receptor (GHSR) in macrophages plays a pivotal role in the development of meta-inflammation, promoting macrophage infiltration and pro-inflammatory ...
Peiu SN +11 more
europepmc +2 more sources
Smartphone based music intervention in the treatment of episodic migraine headaches – A pilot trial
Objectives: Migraine headaches are a prevalent and burdening disorder for the public worldwide. Both traditional preventive drugs and behavioral-based interventions have been used as treatment in the prevention of migraine attacks.
Guilhem Parlongue +3 more
doaj +1 more source
Abstract While evidence is emerging that the temporal pattern of feeding may influence anxiety, it is unclear to what extent anxiety may itself impact spontaneous feeding behaviour. To address this, we have quantified spontaneous feeding, ghrelin secretion and adult hippocampal neurogenesis (AHN) in male low (LAB) and high (HAB) anxiety‐behaviour rats.
Amanda K. E. Hornsby +8 more
wiley +1 more source
Nucleotide polymorphisms of the bovine growth hormone secretagogue receptor 1a (GHSR1a) gene and their association with growth and carcass traits in Japanese Black cattle [PDF]
Ghrelin growth hormone secretagogue receptor 1a (GHSR1a) is involved in many important functions, including growth hormone secretion and food intake (Howard et al. 1996).
Fujimori, Y +6 more
core +3 more sources
Abstract The neuroendocrine control of growth is mediated by the hypothalamic–pituitary–somatic (HPS) axis. This involves the hypothalamic release of growth hormone‐releasing hormone (GHRH), which stimulates the pituitary secretion of growth hormone (GH).
Bradley B. Jamieson
wiley +1 more source
Endogenous production of ghrelin and beneficial effects of its exogenous administration in monocrotaline-induced pulmonary hypertension [PDF]
We investigated the endogenous production of ghrelin as well as cardiac and pulmonary vascular effects of its administration in a rat model of monocrotaline (MCT)-induced pulmonary hypertension (PH).
Baptista, MJ +9 more
core +1 more source
Growth hormone (GH)‐releasing peptides (GHRPs) regulate growth and immune responses in fish, offering potential aquaculture applications. This study evaluated the effects of GHRP‐6 and its recombinant analog, F5WAC (acetylation of the N‐terminal Histidine [His1] and substitution of D‐Phenylalanine with D‐Tryptophan at position 5), on growth performance,
AbdolMajid Valipour +3 more
wiley +1 more source
Expression of Ghrelin and GHSR-1a in Long Term Diabetic Rat's Kidney [PDF]
The aim of this work was to study the relative ghrelin and growth hormone secretagogue receptor (GHS-R)1a gene expression in the kidney of long-term diabetic rats. Forty male Wistar albino rats were divided into four groups: C- control group, DI- one month diabetic rats group, DII- two months diabetic rats group, and DIII- three months diabetic rats ...
Yildirim, Aysegul Burcin +4 more
openaire +4 more sources
Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits [PDF]
The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases including ...
Aschard, H. (Hugues) +85 more
core +1 more source

