Results 81 to 90 of about 8,260 (216)
Molecular MetabolismObjective: Obesity-associated chronic inflammation, aka meta-inflammation, is a key pathogenic driver for obesity-associated comorbidity. Growth hormone secretagogue receptor (GHSR) is known to mediate the effects of nutrient-sensing hormone ghrelin in ...
Da Mi Kim +13 more
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JCI Insight, 2023 Previous studies have implicated the orexigenic hormone ghrelin as a mediator of exercise endurance and the feeding response postexercise. Specifically, plasma ghrelin levels nearly double in mice when they are subjected to an hour-long bout of high ...
Omprakash Singh +11 more
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Mutations in the ghrelin receptor gene GHSR in congenital hypopituitarism
Problems of Endocrinology, 2017 The results of molecular genetic studies indicate the potential involvement of ghrelin in the pathogenesis of some dwarfism forms. However, in the case of isolated somatotropin insufficiency, mutations in the ghrelin receptor gene are a rare cause of the disease.
Elena B. Bashnina +6 more
openaire +2 more sources
Chloride Balance in Preterm Infants during the First Week of Life
International Journal of Pediatrics, 2012 Objective. To describe the chloride balance in infants born 25–32-week gestation, analyze the association of chloride changes with hydroelectrolytic status and their relationship with perinatal conditions, morbidities, and neurological outcome.
Silvia Iacobelli +4 more
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A Sleep‐Specific Midbrain Target for Sevoflurane Anesthesia
Advanced Science, 2023 Sevoflurane has been the most widely used inhaled anesthetics with a favorable recovery profile; however, the precise mechanisms underlying its anesthetic action are still not completely understood.
Tingting Yi +21 more
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Relationship between abnormal symptoms of Prader-Willi syndrome model --Snord116 deletion mice and Ghrelin signaling pathway [PDF]
, 2016 Prader–Willi综合症是以进食异常和血液Ghrelin异常升高为特征的遗传肥胖症。其病因是Snord116SnoRNA群的表达缺失。我们构建的Snord116del小鼠模型表现出贪食和血液Ghrelin升高等PWS症状。此次研究中，我们繁育野生型（WT）、Snord116del（SW）、Ghrl-/-（WG）、Ghsr-/-（WR）小鼠，并制备[Snord116del，Ghrl-/-]（SG）和[Snord116del，Ghsr-/-]（SR）双敲除小鼠，对其生长发育 ...
甘利芬
core
Molecular and Neuroendocrine Determinants of Seasonal Body Weight Regulation [PDF]
, 2005 This thesis deals with the characterisation of neuroendocrine pathways involved in seasonal body regulation revealed by the Siberian hamster (Phodopus sungorus).
Klingenspor, Martin (Dr.) +1 more
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Ghrelin enhances tubular magnesium absorption in the kidney
Frontiers in PhysiologyOsteoporosis after bariatric surgery is an increasing health concern as the rate of bariatric surgery has risen. In animal studies mimicking bariatric procedures, bone disease, together with decreased serum levels of Ca2+, Mg2+ and the gastric hormone ...
Mingzhu Nie +11 more
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Constitutive and ghrelin-dependent GHSR1a activation impairs CaV2.1 and CaV2.2 currents in hypothalamic neurons [PDF]
, 2015 The growth hormone secretagogue receptor type 1a (GHSR1a) has the highest constitutive activity of any G protein coupled receptor (GPCR). GHSR1a mediates the action of the hormone ghrelin and, its activation increases transcriptional and electrical ...
Agosti +76 more
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Folia Histochemica et Cytobiologica, 2010 The results of presented study demonstrate expression of ghrelin, its functional receptor GHSR-1a and their genes in spermatogenic cells of rat testis suggesting their functioning within seminiferous epithelium.
Marcin Ruciński +7 more
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