Results 81 to 90 of about 8,222 (228)

Brain circuits mediating the orexigenic action of peripheral ghrelin: narrow gates for a vast kingdom [PDF]

open access: yes, 2015
The nervous and endocrine systems act together to regulate all physiological processes essential for the body homeostasis control. Given the strict communication restrictions that the brain–blood barrier (BBB) imposes, the interplay between these two ...
Cabral, Agustina   +2 more
core   +6 more sources

Catestatin and GABAAR related feeding habits rely on dopamine, ghrelin plus leptin neuroreceptor expression variations [PDF]

open access: yes, 2016
Catestatin (CST), an endogenously small sympathoinhibitory peptide is capable of interfering with the major cerebral neuroreceptor-blocking site, i.e. γ-aminobutyric acidA receptor (GABAAR) system especially in limbic brain areas that are involved with ...
Alò, Raffaella   +7 more
core   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

Integrating the inputs that shape pancreatic islet hormone release. [PDF]

open access: yes, 2019
The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
core  

Insight Into Body Size Evolution in Aves: Based on Some Body Size‐Related Genes

open access: yesIntegrative Zoology, Volume 20, Issue 6, Page 1124-1135, November 2025.
These findings provide new insights into the genetic determinants of body size evolutionary mechanisms in Aves. ABSTRACT Birds exhibit remarkable variations in body size, making them an ideal group for the study of adaptive evolution. However, the genetic mechanisms underlying body size evolution in avian species remain inadequately understood.
Chaoyang Luo   +8 more
wiley   +1 more source

Molecular and Neuroendocrine Determinants of Seasonal Body Weight Regulation [PDF]

open access: yes, 2005
This thesis deals with the characterisation of neuroendocrine pathways involved in seasonal body regulation revealed by the Siberian hamster (Phodopus sungorus).
Klingenspor, Martin (Dr.)   +1 more
core   +1 more source

Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

open access: yesCommunications Biology
The stomach-derived hormone ghrelin regulates essential physiological functions. The ghrelin receptor (GHSR) has ligand-independent actions; therefore, GHSR gene deletion may be a reasonable approach to investigate the role of this system in feeding ...
András H. Lékó   +22 more
doaj   +1 more source

Neuronal ablation of GHSR mitigates diet-induced depression and memory impairment via AMPK-autophagy signaling-mediated inflammation

open access: yesFrontiers in Immunology
Obesity is associated with chronic inflammation in the central nervous system (CNS), and neuroinflammation has been shown to have detrimental effects on mood and cognition.
Hongying Wang   +15 more
doaj   +1 more source

Ghrelin mediates exercise endurance and the feeding response post-exercise

open access: yesMolecular Metabolism, 2018
Objective: Exercise training has several well-established health benefits, including many related to body weight, appetite control, and blood glucose homeostasis. However, the molecular mechanisms and, in particular, the hormonal systems that mediate and
Bharath K. Mani   +6 more
doaj   +1 more source

Ghrelin-responsive mediobasal hypothalamic neurons mediate exercise-associated food intake and exercise endurance

open access: yesJCI Insight, 2023
Previous studies have implicated the orexigenic hormone ghrelin as a mediator of exercise endurance and the feeding response postexercise. Specifically, plasma ghrelin levels nearly double in mice when they are subjected to an hour-long bout of high ...
Omprakash Singh   +11 more
doaj   +1 more source

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