Results 71 to 80 of about 6,246 (170)
α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling
Frontiers in Cellular Neuroscience, 2017 α-Synuclein is a presynaptic protein that regulates synaptic vesicle (SV) trafficking. In Parkinson’s disease (PD) and several other neurodegenerative disorders, aberrant oligomerization and aggregation of α-synuclein lead to synaptic dysfunction and ...
Audrey T. Medeiros +4 more
doaj +1 more source
A chloride channel from human placenta reconstituted into giant liposomes
American Journal of Obstetrics and Gynecology, 1995 Ion channels play important roles in epithelial transport, but they are difficult to access for conventional electrophysiologic studies in intact placenta. The purpose of this work was to explore the suitability of purified trophoblast plasma membrane as a source of ion channels for reconstitution in artificial lipid membranes.Human placental brush ...
Riquelme, Gloria +3 more
openaire +3 more sources
Nature CommunicationsThe spatial and temporal dynamics of forces in cells coordinate essential behaviors like division, polarization, and migration. While intracellular signaling initiates contractile ring assembly during cell division, how mechanical forces coordinate ...
Ryota Sakamoto, Michael P. Murrell
doaj +1 more source
PLoS ONE, 2019 R-DIM-P-LF11-322 and DIM-LF11-318, derived from the cationic human host defense peptide lactoferricin show antitumor activity against human melanoma. While R-DIM-P-LF11-322 interacts specifically with cancer cells, the non-specific DIM-LF11-318 exhibits ...
Christina Wodlej +8 more
doaj +1 more source
Adsorption and Fluctuations of Giant Liposomes Studied by Electrochemical Impedance Measurements
Langmuir, 2005 The present study describes a novel approach based on electrochemical impedance measurements to follow the adsorption of giant liposomes on protein-coated solid surfaces with a time resolution in the order of seconds. The technical key features are circular gold-film electrodes as small as a few hundred micrometers in diameter and measurements of the ...
Sapper, Angelika +3 more
openaire +3 more sources
Advanced ScienceCell membranes play a key role in bottom‐up synthetic biology, as they enable interaction control, transport, and other essential functions. These ultra‐thin, flexible, yet stable structures form through the self‐assembly of lipids and proteins.
Dominik Söder +8 more
doaj +1 more source
BiophysicaDrug delivery systems play a pivotal role in targeted pharmaceutical transport and controlled release at specific sites. Liposomes, commonly used as drug carriers, constitute a fundamental part of these systems.
Kristina Bruun +2 more
doaj +1 more source
Cell Reports: MethodsSummary: This paper reports an effective protocol to encapsulate native protein/DNA complexes into unilamellar vesicles composed of natural lipids without the use of organic solvents, in physiological buffers, and at low protein/DNA concentrations.
Michael Burger +3 more
doaj +1 more source
Shadow electrochemiluminescence imaging of giant liposomes opening at polarized electrodes
The AnalystIn this work, the release of giant liposome (∼100 μm in diameter) content was imaged by shadow electrochemiluminescence (ECL) microscopy.
Ben Trad, Fatma +7 more
openaire +3 more sources
Diffusion of Single-Pass Transmembrane Receptors: From the Plasma Membrane into Giant Liposomes. [PDF]
J Membr Biol, 2017 Worch R +3 more
europepmc +1 more source