Results 51 to 60 of about 465,440 (235)

Multiple Membrane Interactions and Versatile Vesicle Deformations Elicited by Melittin

open access: yesToxins, 2013
Melittin induces various reactions in membranes and has been widely studied as a model for membrane-interacting peptide; however, the mechanism whereby melittin elicits its effects remains unclear. Here, we observed melittin-induced changes in individual
Kingo Takiguchi   +5 more
doaj   +1 more source

Giant Liposome Preparation for Imaging and Patch-Clamp Electrophysiology

open access: yesJournal of Visualized Experiments, 2013
The reconstitution of ion channels into chemically defined lipid membranes for electrophysiological recording has been a powerful technique to identify and explore the function of these important proteins. However, classical preparations, such as planar bilayers, limit the manipulations and experiments that can be performed on the reconstituted channel
Marcus D, Collins, Sharona E, Gordon
openaire   +3 more sources

Glucocorticoids—All-Rounders Tackling the Versatile Players of the Immune System [PDF]

open access: yes, 2019
Glucocorticoids regulate fundamental processes of the human body and control cellular functions such as cell metabolism, growth, differentiation, and apoptosis.
Agarwal   +268 more
core   +1 more source

Biomimetic soft matter [PDF]

open access: yes, 2011
Biomaterials are often soft materials. There is now growing interest in designing, synthesizing and characterising soft materials that mimic the properties of biological materials such as tissue, proteins, DNA or cells. Research on biomimetic soft matter
Hamley, Ian
core   +1 more source

Droplet-Based Microfluidics as a Platform to Design Food-Grade Delivery Systems Based on the Entrapped Compound Type

open access: yesFoods, 2023
Microfluidic technology has emerged as a powerful tool for several applications, including chemistry, physics, biology, and engineering. Due to the laminar regime, droplet-based microfluidics enable the development of diverse delivery systems based on ...
Jhonatan Rafael de Oliveira Bianchi   +2 more
doaj   +1 more source

ESCRT-III mediated cell division in Sulfolobus acidocaldarius - a reconstitution perspective [PDF]

open access: yes, 2014
In the framework of synthetic biology, it has become an intriguing question what would be the minimal representation of cell division machinery. Thus, it seems appropriate to compare how cell division is realized in different microorganisms. Inparticular,
Härtel, T., Schwille, P.
core   +2 more sources

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

open access: yesAdvanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo   +9 more
wiley   +1 more source

Native silica nanoparticles are powerful membrane disruptors [PDF]

open access: yes, 2015
Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I.   +3 more
core   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

open access: yesAdvanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai   +8 more
wiley   +1 more source

Phagocytosis in Mesocestoides vogae-induced peritoneal monocytes/macrophages via opsonin-dependent or independent pathways

open access: yesHelminthologia, 2016
Intraperitoneal infection with larvae of cestode Mesocestoides vogae offers the opportunity to study dynamic changes in the proportion and functions of individual cell types under a direct influence of parasites.
Hrčková G., Vendelova E., Velebný S.
doaj   +1 more source

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