Line tensions, correlation lengths, and critical exponents in lipid membranes near critical points
Membranes containing a wide variety of ternary mixtures of high chain-melting temperature lipids, low chain-melting temperature lipids, and cholesterol undergo lateral phase separartion into coexisting liquid phases at a miscibility transition.
Cicuta, Pietro+6 more
core +1 more source
Self-Assembly Behavior of Amphiphilic Janus Dendrimers in Water: A Combined Experimental and Coarse-Grained Molecular Dynamics Simulation Approach [PDF]
Indexación: Scopus.Acknowledgments: M.E.E.G. thank the Ph. D. scholarship (251115) from CONACyT. The authors would like to thank: Luis Elizalde-Herrera (CIQA) for his help running the NMR spectra; Gloria Macedo-Raygoza and Miguel J. Beltrán-García (UAG),
Araya-Durán, I.+4 more
core +1 more source
Interactions of apolipoprotein A-I (apoA-I) with cell membranes appear to be important in the initial steps of reverse cholesterol transport. The objective of this work was to examine the effect of three distinct conformations of apoA-I (lipid-free and ...
M. Alejandra Tricerri+5 more
doaj
Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard+7 more
wiley +1 more source
Charge-induced phase separation in lipid membranes [PDF]
The phase separation in lipid bilayers that include negatively charged lipids is examined experimentally. We observed phase-separated structures and determined the membrane miscibility temperatures in several binary and ternary lipid mixtures of ...
Andelman, David+5 more
core +2 more sources
Artificial membrane-like environments for in vitro studies of purified G-protein coupled receptors [PDF]
Functional reconstitution of transmembrane proteins remains a significant barrier to their biochemical, biophysical, and structural characterization. Studies of seven-transmembrane G-protein coupled receptors (GPCRs) in vitro are particularly challenging
Serebryany, Eugene+2 more
core +1 more source
Peptide and nucleic acid-directed self-assembly of cationic nanovehicles through giant unilamellar vesicle modification: targetable nanocomplexes for in vivo nucleic acid delivery [PDF]
One of the greatest challenges for the development of genetic therapies is the efficient targeted delivery of therapeutic nucleic acids. Towards this goal, we have introduced a new engineering initiative in self-assembly of biologically safe and stable ...
A.D. Tagalakis+77 more
core +2 more sources
A membrane filtering method for the purification of giant unilamellar vesicles
The use of giant unilamellar vesicles (GUVs) for investigating the properties of biomembranes is advantageous compared to the use of small-sized vesicles such as large unilamellar vesicles (LUVs). Experimental methods using GUVs, such as the single GUV method, would benefit if there was a methodology for obtaining a large population of similar-sized ...
Yukihiro Tamba+2 more
openaire +3 more sources
In vitro investigation of the interaction between proteins and positively curved membranes can be performed using a classic nanotube pulling method.
Nicola Franceschi+3 more
doaj +1 more source
Spontaneous Expulsion of Giant Lipid Vesicles Induced by Laser Tweezers [PDF]
Irradiation of a giant unilamellar lipid bilayer vesicle with a focused laser spot leads to a tense pressurized state which persists indefinitely after laser shutoff. If the vesicle contains another object it can then be gently and continuously expelled from the tense outer vesicle.
arxiv