Rotaxanes with a photoresponsive macrocycle modulate the lipid bilayers of large and giant unilamellar vesicles. [PDF]
Rotaxanes equipped with actuators hold great potential for developing highly functional molecular machines. Such systems could significantly enhance our ability to study and manipulate biological and artificial membranes.
Conthagamage UNK +10 more
europepmc +2 more sources
Chemical communication at the synthetic cell/living cell interface
Synthetic models of cells are becoming increasingly sophisticated, but engineering communication between these and living cells remains challenging. Here the authors review modes of communication and signal processing between living cells and synthetic ...
Vincent Mukwaya +2 more
doaj +1 more source
Proton gradients from light-harvesting E. coli control DNA assemblies for synthetic cells
Controlled actuation is an important aspect of synthetic cellular systems. Here, the authors combine pH responsive DNA origami structures with light triggered proton pump engineered E.
Kevin Jahnke +11 more
doaj +1 more source
Imaging of photoacoustic-mediated permeabilization of giant unilamellar vesicles (GUVs). [PDF]
Target delivery of large foreign materials to cells requires transient permeabilization of the cell membrane without toxicity. Giant unilamellar vesicles (GUVs) mimic the phospholipid bilayer of the cell membrane and are also useful drug delivery ...
Pereira DA +9 more
europepmc +2 more sources
Block Copolymer Giant Unilamellar Vesicles for High-Throughput Screening
Bottom-up synthetic cells offer the potential to study cellular processes with reduced complexity. Giant unilamellar vesicles (GUVs) can mimic cells in their morphological characteristics because their architecture is precisely controllable.
Lukas Heuberger, Cornelia Palivan
doaj +1 more source
Femtoliter Injection of ESCRT-III Proteins into Adhered Giant Unilamellar Vesicles. [PDF]
The endosomal sorting complex required for transport (ESCRT) machinery mediates membrane fission reactions that exhibit a different topology from that observed in clathrin-coated vesicles.
Georgiev VN +3 more
europepmc +2 more sources
Programmed magnetic manipulation of vesicles into spatially coded prototissue architectures arrays
To execute higher-order functions, cells self-assemble into spatially coded tissue configurations. Here the authors magnetically assembly giant unilamellar vesicles into three dimensional tissue-mimic structures with collective osmotic stability.
Qingchuan Li +4 more
doaj +1 more source
Magnetoliposomes as model for signal transmission [PDF]
Liposomes containing magnetic nanoparticles (magnetoliposomes) have been extensively explored for targeted drug delivery. However, the magnetic effect of nanoparticles movement is also an attractive choice for the conduction of signals in communication ...
G. R. Barreto +8 more
doaj +1 more source
Optimized cDICE for Efficient Reconstitution of Biological Systems in Giant Unilamellar Vesicles. [PDF]
Van de Cauter L +9 more
europepmc +3 more sources
Microfluidic production, stability and loading of synthetic giant unilamellar vesicles. [PDF]
In advanced drug delivery, versatile liposomal formulations are commonly employed for safer and more accurate therapies. Here we report a method that allows a straightforward production of synthetic monodisperse (~ 100 μm) giant unilamellar vesicles ...
Ernits M +11 more
europepmc +2 more sources

