Results 51 to 60 of about 114,906 (281)

Genomic analysis of the smallest giant virus — Feldmannia sp. virus 158

open access: yesVirology, 2009
Genomic analysis of Feldmannia sp. virus 158, the second phaeovirus to be sequenced in its entirety, provides further evidence that large double-stranded DNA viruses share similar evolutionary pressures as cellular organisms. Reductive evolution is clearly evident within the phaeoviruses which occurred via several routes: the loss of genes from an ...
Schroeder, Declan C.   +7 more
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Phylogenetic diversity and functional potential of large and cell-associated viruses in the Bay of Bengal

open access: yesmSphere, 2023
The Bay of Bengal (BoB) is the world’s largest bay, offering essential services like fishing and recreation while holding significant economic value for coastal communities. However, the BoB faces environmental challenges from monsoons, freshwater inputs,
Benjamin Minch   +7 more
doaj   +1 more source

Giant Viruses of the Kutch Desert [PDF]

open access: yes, 2014
The Kutch desert (Great Rann of Kutch, Gujarat, India) is a unique ecosystem: in the larger part of the year it is a hot, salty desert that is flooded regularly in the Indian monsoon season.
Grolmusz, Vince, Kerepesi, Csaba
core  

Rabies Vaccination: Higher Failure Rates in Imported Dogs than in those Vaccinated in Italy [PDF]

open access: yes, 2016
The current European Union (EU) legislation decrees that pets entering the EU from a rabies-infected third country have to obtain a satisfactory virus-neutralizing antibody level, while those moving within the EU require only rabies vaccination as the ...
Alonso, S   +7 more
core   +2 more sources

The “Giant Virus Finder” discovers an abundance of giant viruses in the Antarctic dry valleys [PDF]

open access: yesArchives of Virology, 2017
The first giant virus was identified in 2003 from a biofilm of an industrial water-cooling tower in England. Later, numerous new giant viruses were found in oceans and freshwater habitats, some of them having even 2,500 genes. We have demonstrated their very likely presence in four soil samples taken from the Kutch Desert (Gujarat, India).
Csaba Kerepesi, Vince Grolmusz
openaire   +4 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

A Large Open Pangenome and a Small Core Genome for Giant Pandoraviruses

open access: yesFrontiers in Microbiology, 2018
Giant viruses of amoebae are distinct from classical viruses by the giant size of their virions and genomes. Pandoraviruses are the record holders in size of genomes and number of predicted genes. Three strains, P. salinus, P. dulcis, and P.
Sarah Aherfi   +11 more
doaj   +1 more source

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