Mriyaviruses: small relatives of giant viruses. [PDF]
The phylum Nucleocytoviricota consists of large and giant viruses that range in genome size from about 100 kilobases (kb) to more than 2.5 megabases.
Yutin N, Mutz P, Krupovic M, Koonin EV.
europepmc +6 more sources
Giant Viruses—Big Surprises [PDF]
Viruses are the most prevalent infectious agents, populating almost every ecosystem on earth. Most viruses carry only a handful of genes supporting their replication and the production of capsids.
Nadav Brandes, Michal Linial
doaj +4 more sources
Defensive symbiosis against giant viruses in amoebae. [PDF]
Protists are important regulators of microbial communities and key components in food webs with impact on nutrient cycling and ecosystem functioning. In turn, their activity is shaped by diverse intracellular parasites, including bacterial symbionts and ...
Arthofer P +4 more
europepmc +5 more sources
Giant viruses as reservoirs of antibiotic resistance genes. [PDF]
Nucleocytoplasmic large DNA viruses (NCLDVs; also called giant viruses), constituting the phylum Nucleocytoviricota, can infect a wide range of eukaryotes and exchange genetic material with not only their hosts but also prokaryotes and phages.
Yi X +13 more
europepmc +2 more sources
Assessing the biogeography of marine giant viruses in four oceanic transects. [PDF]
Viruses of the phylum Nucleocytoviricota are ubiquitous in ocean waters and play important roles in shaping the dynamics of marine ecosystems. In this study, we leveraged the bioGEOTRACES metagenomic dataset collected across the Atlantic and Pacific ...
Ha AD, Moniruzzaman M, Aylward FO.
europepmc +3 more sources
The discovery of giant viruses has transformed our understanding of viral complexity. Although viruses have traditionally been viewed as filterable infectious agents that lack metabolism, giant viruses can reach sizes rivalling cellular lineages and ...
Anh D. Ha +2 more
doaj +4 more sources
Gene duplication as a major force driving the genome expansion in some giant viruses. [PDF]
Giant viruses with their gigantic genomes are among the most intriguing components of the virosphere. How these viruses attained such giant genomes remains unclear, despite considerable efforts to understand this phenomenon.
Machado TB +20 more
europepmc +2 more sources
Virologs, viral mimicry, and virocell metabolism: the expanding scale of cellular functions encoded in the complex genomes of giant viruses. [PDF]
The phylum Nucleocytoviricota includes the largest and most complex viruses known. These “giant viruses” have a long evolutionary history that dates back to the early diversification of eukaryotes, and over time they have evolved elaborate strategies for
Moniruzzaman M +14 more
europepmc +2 more sources
Giant endogenous viral elements in the genome of the model protist Euglena gracilis reveal past interactions with giant viruses [PDF]
Genomes of giant viruses (phylum Nucleocytoviricota) have increasingly been found integrated into the genomes of diverse eukaryotes. Here, we report eight giant endogenous viral elements (GEVEs) in the genome of the microalgae Euglena gracilis. The GEVEs
Abdeali M. Jivaji +5 more
doaj +2 more sources
Novel High-Quality Amoeba Genomes Reveal Widespread Codon Usage Mismatch Between Giant Viruses and Their Hosts. [PDF]
The need for high-quality protist genomes has prevented in-depth computational and experimental studies of giant virus-host interactions. In addition, our current knowledge of host range is highly biased due to the few hosts used to isolate novel giant ...
Willemsen A, Manzano-Marín A, Horn M.
europepmc +2 more sources

