Results 41 to 50 of about 324,944 (302)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Values of Gifted Specialists as a Professional Identity

Georgia Educational Researcher
Educators of gifted students (gifted specialists) face unique systematic and personal barriers daily. While programs for gifted students are mandated in most states, including Georgia, implementation choices such as identification processes, delivery ...
Bailey Nafziger, Seth Kaesler
doaj   +1 more source

An Investigation into problems encountered by gifted &Talented students and their supervision needs at the pioneers caring centers of Al-Balqa Governorate Jordan. [PDF]

Journal of Islamic Studies, 2010
This study investigated problems encountered by gifted and talented students at the pioneers caring centers in Al-Balqagovcmomteot‘Jordan and their supervision needs.
Omar M. A. Al-Kharabsheh, Ahmad A. Arabyyat   +1 more
doaj  

Factors Affecting the Perceptions and Practices of Differentiated Curricula and Pedagogies for Gifted and Talented Students

Education Sciences, 2022
The definitions and implementation of differentiated curricula and instruction for gifted and talented students have been affected by a myriad of philosophical and institutional factors defined by educators, community members, and gifted and talented ...
Sandra N. Kaplan
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

What would it take? Enhancing outcomes for high-ability students with disability

Frontiers in Education
A troubling misconception exists that high-ability is enough to ensure positive educational, mental health and well-being outcomes for gifted students.
Geraldine Townend, Marie McGregor, Dennis Alonzo, Hoa T. M. Nguyen   +3 more
doaj   +1 more source

Pretense or Belief: Creating Meaningful Scenarios and Simulations for Authentic Learning about Diverse Underserved Gifted Students

Education Sciences, 2022
Understanding of the complexity of gifted students who present with an intersection of unique profiles of abilities and challenges, cultural, ethnic, gender and linguistic perspectives, learning experiences across contexts and personal expectations ...
Gillian Eriksson
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

“Pockets of freedom”: Creating therapeutic spaces as refuges for Black experiences of neurodivergence

International Journal of Narrative Therapy and Community Work
The influence of Eurocentricism on therapy spaces makes them unsafe for Black people. This is compounded for Black people whose lives are impacted by their neurodivergence, and therapeutic support needs to account for that.
Sandra Coral
doaj   +1 more source

Able and gifted: judging by appearances? [PDF]

, 2002
In this article I reflect upon an aspect of my research involving Year 6 pupils identified by their teachers as ‘able’ or ‘gifted’ in mathematics, using ‘able’ to refer to high achievers and ‘gifted’ to exceptionally high achievers.
Briggs, Mary (Mary J.), Wilson, Kirsty
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