Results 61 to 70 of about 77,886 (252)

Gifted children metaphor from the perspective of teachers and parents [PDF]

, 2018
Metaphors help understand how the meanings investigated are perceived (Cerit, 2008; Rizvanoglu, 2007). As may be seen from these statements, metaphors may be regarded as an important tool for identifying the perceptions of teachers and parents of the ...
Kadıoğlu Ateş, Hatice
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Under Pressure: Gifted Students’ Vulnerabilities, Stressors, and Coping Mechanisms Within a High Achieving High School

Behavioral Sciences
This qualitative study explores the interactions among gifted students’ vulnerabilities, stressors, supports, and coping mechanisms at a public, high-achieving residential high school.
Addison Helsper, Lillian DeShon, Laura E. Boylan, James Galliher, Lisa DaVia Rubenstein   +4 more
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Developing a classroom science enrichment programme for gifted primary school boys in Saudi Arabia

, 2011
Enrichment is one of the important educational facilities that are provided for gifted students. However, the research on gifted enrichment programmes still requires further exploration in order to meet the diversity of gifted students.
Alarfaj, Abdulhamid
core   +1 more source

Gifted Education in Ireland: Educators' Beliefs and Practices [PDF]

, 2014
The Irish Centre for Talented Youth has been the sole provider of enrichment programs for gifted children in the country since its foundation in 1992.
Cross, Tracy L., O'Reilly, Colm, Mammadov, Sakhavat, Cross, Jennifer R.   +3 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Knowledge and practice of adults towards different weight loss methods

Rwanda Medical Journal
INTRODUCTION: Obesity has become a major public health issue worldwide. This study assessed knowledge and practices regarding various pharmacological and non-pharmacological weight loss approaches among 393 adults in Iraq.
Raghad O. Aldabbagh, Marwah A. Alshorbaji, Yahya M. Alsabbagh   +2 more
doaj   +1 more source

A Preliminary Study of Satisfaction with University Mentoring in High-Intellectual-Ability Secondary Students: Instrument Validation and Association with Key Learning Processes

Education Sciences
Academic satisfaction is positioned as a fundamental psychological construct with regard to academic success, linked to well-being and cognitive engagement.
Miryam Martínez-Izaguirre, Jon Peña-San José, Alexander Álvarez-González   +2 more
doaj   +1 more source